4XB1

Hyperthermophilic archaeal homoserine dehydrogenase in complex with NADPH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	319aa long hypothetical homoserine dehydrogenase	polymer	335	36975.0	2	UniProt (O58802) Pfam (PF03447) Pfam (PF00742) In PDB	Pyrococcus horikoshii OT3
2	A, B	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	2	Chemie (NDP)
3	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4	A, B	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	5	Chemie (MPD)
5		water	water		18.0	212	Chemie (HOH)

Sequence modifications

A, B: 1 - 319 (UniProt: O58802)

PDB	External Database	Details
Met -15	-	expression tag
Asn -14	-	expression tag
His -13	-	expression tag
Lys -12	-	expression tag
Val -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
Ile -4	-	expression tag
Glu -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73950.0
Non-Polymers*	Number of molecules	9
	Total formula weight	2127.7
All*	Total formula weight	76077.7

*Water molecules are not included.