4XAS

mGluR2 ECD ligand complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Metabotropic glutamate receptor 2	polymer	503	55712.8	2	UniProt (Q14416) Pfam (PF01094) In PDB	Homo sapiens (Human)	mGluR2
2	A, B	(1R,4S,5S,6S)-4-aminospiro[bicyclo[3.1.0]hexane-2,1'-cyclopropane]-4,6-dicarboxylic acid	non-polymer		211.2	2	Chemie (40H)
3		water	water		18.0	207	Chemie (HOH)

Sequence modifications

A, B: 2 - 493 (UniProt: Q14416)

PDB	External Database	Details
Met -1	-	initiating methionine
Ala 0	-	expression tag
Leu 1	-	expression tag
Ser 234	Cys 234	conflict
Glu 302	Ser 302	conflict
Glu 494	-	expression tag
Gly 495	-	expression tag
His 496	-	expression tag
His 497	-	expression tag
His 498	-	expression tag
His 499	-	expression tag
His 500	-	expression tag
His 501	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	111425.7
Non-Polymers*	Number of molecules	2
	Total formula weight	422.4
All*	Total formula weight	111848.1

*Water molecules are not included.