4X99
Immunoglobulin Fc heterodimers variant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ig gamma-1 chain C region | polymer | 223 | 25094.4 | 1 | UniProt (P01857) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
2 | B | Ig gamma-1 chain C region | polymer | 223 | 25080.5 | 1 | UniProt (P01857) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
3 | C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1463.3 | 2 | In PDB GlyTouCan (G80858MF) | |||
4 | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A: 225 - 447 (UniProt: P01857)
B: 225 - 447 (UniProt: P01857)
PDB | External Database | Details |
---|---|---|
Cys 349 | Tyr 232 | engineered mutation |
Glu 360 | Lys 243 | engineered mutation |
Trp 409 | Lys 292 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Arg 347 | Gln 230 | engineered mutation |
Cys 354 | Ser 237 | engineered mutation |
Val 399 | Asp 282 | engineered mutation |
Thr 405 | Phe 288 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 50174.9 | |
Branched | Number of molecules | 2 |
Total formula weight | 2926.7 | |
All* | Total formula weight | 53101.6 |