4X96

Low resolution crystal structure of Lecithin:Cholesterol Acyltransferase (LCAT; residues 21-397)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	D, A, B, C	Phosphatidylcholine-sterol acyltransferase	polymer	383	43690.7	4	UniProt (P04180) Pfam (PF02450) In PDB	Homo sapiens (Human)	Lecithin-cholesterol acyltransferase,Phospholipid-cholesterol acyltransferase
2	E, F, G, H, I...	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	8	In PDB GlyTouCan (G15407YE)
3	D, A, B, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)

Sequence modifications

D, A, B, C: 21 - 400 (UniProt: P04180)

PDB	External Database	Details
His 398	Tyr 422	conflict
His 399	Arg 423	conflict
His 400	Gln 424	conflict
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	174762.9
Branched	Number of molecules	8
	Total formula weight	4692.3
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	180340.1

*Water molecules are not included.