4X8O
Crystal structure of E. coli Adenylate kinase Y171W mutant in complex with inhibitor Ap5a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Adenylate kinase | polymer | 214 | 23643.1 | 2 | UniProt (P69441) Pfam (PF00406) Pfam (PF05191) In PDB | Escherichia coli | AK,ATP-AMP transphosphorylase,ATP:AMP phosphotransferase,Adenylate monophosphate kinase |
| 2 | A, B | BIS(ADENOSINE)-5'-PENTAPHOSPHATE | non-polymer | 916.4 | 2 | Chemie (AP5) | |||
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 214 (UniProt: P69441)
| PDB | External Database | Details |
|---|---|---|
| Trp 171 | Tyr 171 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47286.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1904.3 | |
| All* | Total formula weight | 49190.5 |
