4X7Q
PIM2 kinase in complex with Compound 1s
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Serine/threonine-protein kinase pim-2 | polymer | 312 | 34316.4 | 2 | UniProt (Q9P1W9) Pfam (PF00069) | Homo sapiens (Human) | Pim-2h |
| 2 | C, D (B, A) | 2-(2,6-difluorophenyl)-N-{4-[(3S)-pyrrolidin-3-yloxy]pyridin-3-yl}-1,3-thiazole-4-carboxamide | non-polymer | 402.4 | 2 | Chemie (3YR) | |||
| 3 | E (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | F, G (B, A) | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 311 (UniProt: Q9P1W9)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68632.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 899.8 | |
| All* | Total formula weight | 69532.6 |
