4X6X

Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Bifunctional epoxide hydrolase 2	polymer	336	38646.4	2	UniProt (P34913) Pfam (PF00561) In PDB	Homo sapiens (Human)
2	A, B	3-{4-[(1-{[(1s,2R,3S)-2,3-diphenylcyclopropyl]carbamoyl}piperidin-4-yl)oxy]phenyl}propanoic acid	non-polymer		484.6	2	Chemie (S74)
3		water	water		18.0	191	Chemie (HOH)

Sequence modifications

A, B: 230 - 555 (UniProt: P34913)

PDB	External Database	Details
Met 220	-	expression tag
Lys 221	-	expression tag
Lys 222	-	expression tag
Gly 223	-	expression tag
His 224	-	expression tag
His 225	-	expression tag
His 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77292.8
Non-Polymers*	Number of molecules	2
	Total formula weight	969.2
All*	Total formula weight	78262.0

*Water molecules are not included.