4X5H
ecDHFR complexed with folate and NADP+ at 500 MPa
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydrofolate reductase | polymer | 162 | 18301.6 | 1 | UniProt (P0ABQ4) Pfam (PF00186) In PDB | Escherichia coli K12 | |
| 2 | A | FOLIC ACID | non-polymer | 441.4 | 1 | Chemie (FOL) | |||
| 3 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 4 | A | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 5 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ4)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18301.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1262.9 | |
| All* | Total formula weight | 19564.6 |
