4X51

X-ray structure of mouse interleukin-10 mutant - S1_E8del, C149Y

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Interleukin-10	polymer	162	19222.2	2	UniProt (P18893) Pfam (PF00726)	Mus musculus (House Mouse)	IL-10,Cytokine synthesis inhibitory factor,CSIF
2	C, D (A, B)	water	water		18.0	57	Chemie (HOH)

Sequence modifications

A, B: 9 - 160 (UniProt: P18893)

PDB	External Database	Details
Tyr 149	Cys 167	engineered mutation
Leu 161	-	expression tag
Glu 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag
His 170	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38444.4
All*	Total formula weight	38444.4

*Water molecules are not included.