4X4W

Crystal structure of the full-length human mitochondrial CCA-adding enzyme

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	CCA tRNA nucleotidyltransferase 1, mitochondrial	polymer	416	47877.6	2	UniProt (Q96Q11) Pfam (PF01743) Pfam (PF12627) In PDB	Homo sapiens (Human)	Mitochondrial tRNA nucleotidyl transferase,CCA-adding,mt CCA-adding enzyme,mt tRNA CCA-diphosphorylase,mt tRNA CCA-pyrophosphorylase,mt tRNA adenylyltransferase
2	A, B	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
3	A, B	CITRATE ANION	non-polymer		189.1	2	Chemie (FLC)
4	A, B	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
5	A, B	CHLORIDE ION	non-polymer		35.5	8	Chemie (CL)
6		water	water		18.0	833	Chemie (HOH)

Sequence modifications

A, B: 2 - 408 (UniProt: Q96Q11)

PDB	External Database	Details
Met 1	-	initiating methionine
Leu 409	-	expression tag
Glu 410	-	expression tag
His 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	95755.1
Non-Polymers*	Number of molecules	21
	Total formula weight	1694.7
All*	Total formula weight	97449.8

*Water molecules are not included.