4X49
Crystal structure of the intramolecular trans-sialidase from Ruminococcus gnavus in complex with oseltamivir carboxylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Anhydrosialidase | polymer | 489 | 53992.6 | 1 | UniProt (V8BWT1) | Ruminococcus gnavus ATCC 29149 | |
| 2 | B (A) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 1 | Chemie (G39) | |||
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D, E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | H, I, J (A) | ACETYL GROUP | non-polymer | 44.1 | 3 | Chemie (ACE) | |||
| 6 | K (A) | water | water | 18.0 | 415 | Chemie (HOH) |
Sequence modifications
A: 243 - 723 (UniProt: V8BWT1)
| PDB | External Database | Details |
|---|---|---|
| Gly 235 | - | expression tag |
| Ala 236 | - | expression tag |
| Met 237 | - | expression tag |
| Ala 238 | - | expression tag |
| Asp 239 | - | expression tag |
| Ile 240 | - | expression tag |
| Gly 241 | - | expression tag |
| Ser 242 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 53992.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 825.0 | |
| All* | Total formula weight | 54817.6 |
