4X2Y

Crystal structure of a chimeric Murine Norovirus NS6 protease (inactive C139A mutant) in which the P4-P4 prime residues of the cleavage junction in the extended C-terminus have been replaced by the corresponding residues from the NS2-3 junction.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	NS6 Protease,NS6 Protease	polymer	179	18824.5	2	UniProt (Q80J95) Pfam (PF05416)	Murine norovirus 1
2	C, D (A, B)	water	water		18.0	107	Chemie (HOH)

Sequence modifications

A, B: 4 - 179 (UniProt: Q80J95)

PDB	External Database	Details
Ala 139	Cys 1133	engineered mutation

A, B: 180 - 182 (UniProt: Q80J95)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	37649.0
All*	Total formula weight	37649.0

*Water molecules are not included.