4X2Y
Crystal structure of a chimeric Murine Norovirus NS6 protease (inactive C139A mutant) in which the P4-P4 prime residues of the cleavage junction in the extended C-terminus have been replaced by the corresponding residues from the NS2-3 junction.
Functional Information from GO Data
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: For 3CLpro activity => ECO:0000255|PROSITE-ProRule:PRU00870 |
Chain | Residue | Details |
A | HIS30 | |
A | ALA139 | |
B | HIS30 | |
B | ALA139 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: For 3CLpro activity => ECO:0000303|PubMed:26363064 |
Chain | Residue | Details |
A | ASP54 | |
B | ASP54 |