4X2V
Crystal structure of the Murine Norovirus NS6 protease (inactive C139A mutant) with a C-terminal extension to include residue P1 prime of NS7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NS6 Protease | polymer | 185 | 19368.1 | 4 | UniProt (A0FJD7) Pfam (PF05416) UniProt (by SIFTS) (Q80J95) | Murine norovirus 1 | |
| 2 | E (E) | NS6 Protease | polymer | 5 | 592.6 | 1 | UniProt (Q80J95) | Murine norovirus 1 | |
| 3 | F (F) | NS6 Protease | polymer | 7 | 613.7 | 1 | Murine norovirus 1 | ||
| 4 | G (D) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 5 | H, I, J, K, L (A, B, C, D, E) | water | water | 18.0 | 88 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 184 (UniProt: A0FJD7)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ala 139 | Cys 1133 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 78678.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 69.1 | |
| All* | Total formula weight | 78748.0 |
