4X1Q
The crystal structure of mupain-1 in complex with murinised human uPA at pH7.4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (P) | mupain-1 | polymer | 10 | 1191.4 | 1 | synthetic construct | ||
| 2 | B (U) | Urokinase-type plasminogen activator | polymer | 247 | 27869.7 | 1 | UniProt (P00749) Pfam (PF00089) | Homo sapiens (Human) | uPA |
| 3 | C (U) | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence modifications
U: 16 - 244 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Tyr 99 | His 272 | engineered mutation |
| Ala 122 | Cys 299 | engineered mutation |
| Gln 145 | Asn 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29061.1 | |
| All* | Total formula weight | 29061.1 |
