4X0P

Ternary complex of human DNA polymerase theta C-terminal domain binding ddATP opposite a tetrahydrofuran AP site analog

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	DNA polymerase theta	polymer	799	89585.6	4	UniProt (O75417) Pfam (PF00476)	Homo sapiens (Human)	DNA polymerase eta
2	E, G, I, K (F, H, J, L)	DNA (5'-D(P*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*C)-3')	polymer	13	3958.6	4		synthetic construct
3	F, H, J, L (E, G, I, K)	DNA (5'-D(*CP*GP*TP*TP*GP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3')	polymer	18	5541.6	4		synthetic construct
4	M, N, Q, R, U... (A, B, C, D)	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
5	AA, O, S, W (D, A, B, C)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
6	BA, P, T, X (D, A, B, C)	2',3'-dideoxyadenosine triphosphate	non-polymer		475.2	4	Chemie (DDS)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	396342.9
Non-Polymers*	Number of molecules	16
	Total formula weight	2797.8
All*	Total formula weight	399140.7

*Water molecules are not included.