4WZQ

Mutant K20E of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA dependent-RNA polymerase 3D	polymer	481	54177.3	1	UniProt (A4H1Z0) Pfam (PF00680) UniProt (by SIFTS) (P03311)	Foot-and-mouth disease virus
2	B (B)	RNA template	polymer	8	2541.6	1		synthetic construct
3	C (C)	RNAprimer	polymer	7	2212.4	1		synthetic construct
4	D (A)	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
5	E, F (A, C)	water	water		18.0	12	Chemie (HOH)

Sequence modifications

A: 1 - 470 (UniProt: A4H1Z0)

PDB	External Database	Details
Glu 20	Lys 1877	engineered mutation
Ala 471	-	expression tag
Ala 472	-	expression tag
Leu 473	-	expression tag
Glu 474	-	expression tag
His 475	-	expression tag
His 476	-	expression tag
His 477	-	expression tag
His 478	-	expression tag
His 479	-	expression tag
His 480	-	expression tag
His 481	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	58931.3
Non-Polymers*	Number of molecules	1
	Total formula weight	54.9
All*	Total formula weight	58986.2

*Water molecules are not included.