4WZ9

APN1 from Anopheles gambiae

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	AGAP004809-PA	polymer	957	107443.6	2	UniProt (Q7Q2T8) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838)	Anopheles gambiae (African malaria mosquito)
2	C (M)	ALA-ALA-ALA-LYS-ALA	polymer	5	431.5	1		Drosophila
3	D (N)	ALA-ALA-LYS	polymer	3	289.4	1		Drosophila
4	E, I (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
5	F, G, J, K, L (A, B)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
6	H (A)	2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID	non-polymer		207.3	1	Chemie (NHE)
7	M (B)	COPPER (II) ION	non-polymer		63.5	1	Chemie (CU)
8	N, O (A, B)	water	water		18.0	146	Chemie (HOH)

Sequence modifications

A, B: 22 - 945 (UniProt: Q7Q2T8)

PDB	External Database	Details
Arg 18	-	expression tag
Ser 19	-	expression tag
Pro 20	-	expression tag
Trp 21	-	expression tag
Ala 943	Phe 943	conflict
Arg 946	-	expression tag
Gly 947	-	expression tag
His 948	-	expression tag
Pro 949	-	expression tag
Phe 950	-	expression tag
Glu 951	-	expression tag
Gly 952	-	expression tag
Lys 953	-	expression tag
Pro 954	-	expression tag
Ile 955	-	expression tag
Pro 956	-	expression tag
Asn 957	-	expression tag
Pro 958	-	expression tag
Leu 959	-	expression tag
Leu 960	-	expression tag
Gly 961	-	expression tag
Leu 962	-	expression tag
Asp 963	-	expression tag
Ser 964	-	expression tag
Thr 965	-	expression tag
Arg 966	-	expression tag
Thr 967	-	expression tag
Gly 968	-	expression tag
His 969	-	expression tag
His 970	-	expression tag
His 971	-	expression tag
His 972	-	expression tag
His 973	-	expression tag
His 974	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	215608.0
Non-Polymers*	Number of molecules	9
	Total formula weight	862.1
All*	Total formula weight	216470.1

*Water molecules are not included.