4WYM
Structural basis of HIV-1 capsid recognition by CPSF6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Capsid protein p24 | polymer | 231 | 25461.3 | 12 | UniProt (P12497) Pfam (PF00607) Pfam (PF19317) UniProt (by SIFTS) (P12493) | Human immunodeficiency virus type 1 group M subtype B (HIV-1) | Pr55Gag |
| 2 | M, N, O, P, Q... (M, N, O, P, Q...) | ISOFORM 2 OF CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6 | polymer | 17 | 1709.0 | 11 | UniProt (Q16630) | Homo sapiens (Human) | Cleavage and polyadenylation specificity factor 68 kDa subunit,CPSF 68 kDa subunit,Pre-mRNA cleavage factor Im 68 kDa subunit,Protein HPBRII-4/7 |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 231 (UniProt: P12497)
M, N, O, P, Q, R, S, T, U, V, W: 313 - 327 (UniProt: Q16630)
| PDB | External Database | Details |
|---|---|---|
| Cys 14 | Ala 146 | engineered mutation |
| Cys 45 | Glu 177 | engineered mutation |
| Ala 184 | Trp 316 | engineered mutation |
| Ala 185 | Met 317 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 311 | - | expression tag |
| Thr 312 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 23 |
| Total formula weight | 324333.7 | |
| All* | Total formula weight | 324333.7 |
