4WYL

Mutant K18E of 3D polymerase from Foot-and-Moth Disease Virus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA-directed RNA polymerase 3D-POL	polymer	481	54177.3	1	UniProt (P03311) Pfam (PF00680) In PDB	Foot-and-mouth disease virus (FMDV)
2	A	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
3	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
4	A	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
5		water	water		18.0	147	Chemie (HOH)

Sequence modifications

A: 1 - 470 (UniProt: P03311)

PDB	External Database	Details
Glu 18	Lys 1875	engineered mutation
Ala 471	-	expression tag
Ala 472	-	expression tag
Leu 473	-	expression tag
Glu 474	-	expression tag
His 475	-	expression tag
His 476	-	expression tag
His 477	-	expression tag
His 478	-	expression tag
His 479	-	expression tag
His 480	-	expression tag
His 481	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	54177.3
Non-Polymers*	Number of molecules	5
	Total formula weight	390.3
All*	Total formula weight	54567.6

*Water molecules are not included.