4WXX
The crystal structure of human DNMT1(351-1600)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | DNA (cytosine-5)-methyltransferase 1 | polymer | 1256 | 142102.0 | 2 | UniProt (P26358) Pfam (PF12047) Pfam (PF02008) Pfam (PF01426) Pfam (PF00145) In PDB | Homo sapiens (Human) | Dnmt1, CXXC-type zinc finger protein 9, DNA methyltransferase HsaI, MCMT |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 3 | A, B | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 4 | water | water | 18.0 | 637 | Chemie (HOH) |
Sequence modifications
A, B: 351 - 1600 (UniProt: P26358)
| PDB | External Database | Details |
|---|---|---|
| Ser 350 | - | expression tag |
| Leu 1601 | - | expression tag |
| Thr 1602 | - | expression tag |
| Arg 1603 | - | expression tag |
| Val 1604 | - | expression tag |
| Trp 1605 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 284204.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1422.9 | |
| All* | Total formula weight | 285626.9 |
