4WXX
The crystal structure of human DNMT1(351-1600)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA (cytosine-5)-methyltransferase 1 | polymer | 1256 | 142102.0 | 2 | UniProt (P26358) Pfam (PF12047) Pfam (PF02008) Pfam (PF01426) Pfam (PF00145) | Homo sapiens (Human) | Dnmt1, CXXC-type zinc finger protein 9, DNA methyltransferase HsaI, MCMT |
| 2 | C, D, E, F, G... (A, B) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 3 | H, N (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 4 | O, P (A, B) | water | water | 18.0 | 637 | Chemie (HOH) |
Sequence modifications
A, B: 351 - 1600 (UniProt: P26358)
| PDB | External Database | Details |
|---|---|---|
| Ser 350 | - | expression tag |
| Leu 1601 | - | expression tag |
| Thr 1602 | - | expression tag |
| Arg 1603 | - | expression tag |
| Val 1604 | - | expression tag |
| Trp 1605 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 284204.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1422.9 | |
| All* | Total formula weight | 285626.9 |
