4WXF

Crystal structure of L-Serine Hydroxymethyltransferase in complex with glycine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, C)	Serine hydroxymethyltransferase	polymer	428	46543.5	2	UniProt (Q5M0B4)	Streptococcus thermophilus	Serine methylase
2	C, F (A, C)	N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]	non-polymer		306.2	2	Chemie (PLG)
3	D, E (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	G, H (A, C)	water	water		18.0	349	Chemie (HOH)

Sequence modifications

A, C: 1 - 416 (UniProt: Q5M0B4)

PDB	External Database	Details
Met -11	-	initiating methionine
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	93087.1
Non-Polymers*	Number of molecules	4
	Total formula weight	796.6
All*	Total formula weight	93883.7

*Water molecules are not included.