4WU8

Structure of trPtNAP-NCP145

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	I	DNA (145-MER)	polymer	145	44749.7	1		synthetic construct
2	J	DNA (145-MER)	polymer	145	44740.6	1		synthetic construct
3	A, E	Histone H3.2	polymer	135	15303.9	2	UniProt (P84233) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)
4	B, F	Histone H4	polymer	102	11263.2	2	UniProt (P62799) Pfam (PF15511) In PDB	Xenopus laevis (African clawed frog)
5	C, G	Histone H2A type 1	polymer	129	13978.2	2	UniProt (P06897) Pfam (PF00125) Pfam (PF16211) In PDB	Xenopus laevis (African clawed frog)
6	D, H	Histone H2B 1.1	polymer	125	13848.1	2	UniProt (P02281) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)	H2B1.1
7	I, J	[2-(3-{bis[2-(amino-kappaN)ethyl]amino-kappaN}propyl)-1H-benzo[de]isoquinoline-1,3(2H)-dionato(2-)]platinum(1+)	non-polymer		533.5	2	Chemie (CX3)
8	D, H	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
9	E	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
10		water	water		18.0	36	Chemie (HOH)

Sequence modifications

A, E: 1 - 135 (UniProt: P84233)

PDB	External Database	Details
Ala 102	Gly 103	engineered mutation

C, G: 1 - 129 (UniProt: P06897)

PDB	External Database	Details
Arg 99	Gly 100	engineered mutation
Ser 123	Ala 124	engineered mutation

D, H: -2 - 122 (UniProt: P02281)

PDB	External Database	Details
Thr 29	Ser 33	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	198277.3
Non-Polymers*	Number of molecules	5
	Total formula weight	1283.4
All*	Total formula weight	199560.7

*Water molecules are not included.