4WSQ
Crystal Structure of Adaptor Protein 2 Associated Kinase (AAK1) in complex with small molecule inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | AP2-associated protein kinase 1 | polymer | 317 | 35744.1 | 2 | UniProt (Q2M2I8) Pfam (PF00069) | Homo sapiens (Human) | Adaptor-associated kinase 1 |
| 2 | C, D, E, H, I... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | G, K (A, B) | K-252A | non-polymer | 467.5 | 2 | Chemie (KSA) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 285 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71488.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1389.5 | |
| All* | Total formula weight | 72877.6 |
