4WSQ
Crystal Structure of Adaptor Protein 2 Associated Kinase (AAK1) in complex with small molecule inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | AP2-associated protein kinase 1 | polymer | 317 | 35744.1 | 2 | UniProt (Q2M2I8) Pfam (PF00069) | Homo sapiens (Human) | Adaptor-associated kinase 1 |
| 2 | C, D, E, H, I... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | G, K (A, B) | K-252A | non-polymer | 467.5 | 2 | Chemie (KSA) PubChem (3813) PubChem (24867866) PubChem (49868185) PubChem (3035817) PubChem (490561) PubChem (127357) PubChem (6610352) PubChem (98053103) PubChem (98118654) PubChem (101713437) PubChem (102446520) PubChem (9890741) PubChem (9912410) PubChem (9912412) PubChem (9912413) PubChem (11612445) PubChem (162981511) PubChem (144411107) PubChem (162981512) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 285 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71488.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1389.5 | |
| All* | Total formula weight | 72877.6 |
