4WRZ

Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 5-fluorouracil (AB), Form I

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Uracil-DNA glycosylase	polymer	238	25813.5	1	UniProt (P9WFQ9) Pfam (PF03167) In PDB	Mycobacterium tuberculosis	UDG
2	A	CITRIC ACID	non-polymer		192.1	1	Chemie (CIT)
3	A	5-FLUOROURACIL	non-polymer		130.1	1	Chemie (URF)
4	A	ISOPROPYL ALCOHOL	non-polymer		60.1	1	Chemie (IPA)
5	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6		water	water		18.0	385	Chemie (HOH)

Sequence modifications

A: 1 - 227 (UniProt: P9WFQ9)

PDB	External Database	Details
Met -10	-	initiating methionine
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Gly -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	25813.5
Non-Polymers*	Number of molecules	4
	Total formula weight	417.7
All*	Total formula weight	26231.3

*Water molecules are not included.