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4WRO

Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, JB
(13, 1G)
16S ribosomal RNApolymer1522493958.32GenBank (155076)Thermus thermophilus HB8
2B, CA, D
(1L, 3L, 3K)
tRNA-Phepolymer7624635.93Escherichia coli K-12
3BA, C
(2L, 2K)
tRNA-fMetpolymer7724850.02Escherichia coli K-12
4DA, E
(4L, 4K)
RNA (30-MER)polymer309802.02Thermus thermophilus HB8
5EA, F
(14, 1H)
23S ribosomal RNApolymer2917948539.92GenBank (48268)Thermus thermophilus HB8
6G, KB
(1E, 12)
30S ribosomal protein S2polymer25629317.72UniProt (P80371)
Pfam (PF00318)
Thermus thermophilus HB8
7H, LB
(2E, 22)
30S ribosomal protein S3polymer23926751.12UniProt (P80372)
Pfam (PF07650)
Pfam (PF00189)
Thermus thermophilus HB8
8I, MB
(3E, 32)
30S ribosomal protein S4polymer20924373.42UniProt (P80373)
Pfam (PF00163)
Pfam (PF01479)
Thermus thermophilus HB8
9J
(4E)
30S ribosomal protein S5polymer16217583.41UniProt (Q5SHQ5)
Pfam (PF00333)
Pfam (PF03719)
Thermus thermophilus HB8
10K
(5E)
30S ribosomal protein S6polymer10111988.81UniProt (Q5SLP8)
Pfam (PF01250)
Thermus thermophilus HB8TS9
11L
(6E)
30S ribosomal protein S7polymer15618051.01UniProt (P17291)
Pfam (PF00177)
Thermus thermophilus HB8
12M
(7E)
30S ribosomal protein S8polymer13815868.61UniProt (Q5SHQ2)
Pfam (PF00410)
UniProt (by SIFTS) (P0DOY9)
Thermus thermophilus HB8
13N
(8E)
30S ribosomal protein S9polymer12814410.61UniProt (P80374)
Pfam (PF00380)
Thermus thermophilus HB8
14O
(1I)
30S ribosomal protein S10polymer10511955.01UniProt (Q5SHN7)
Pfam (PF00338)
Thermus thermophilus HB8
15P
(2I)
30S ribosomal protein S11polymer12913737.91UniProt (P80376)
Pfam (PF00411)
Thermus thermophilus HB8
16Q
(3I)
30S ribosomal protein S12polymer13214637.41UniProt (Q5SHN3)
Pfam (PF00164)
Thermus thermophilus HB8
17R
(4I)
30S ribosomal protein S13polymer12614352.91UniProt (P80377)
Pfam (PF00416)
Thermus thermophilus HB8
18S
(5I)
30S ribosomal protein S14 type Zpolymer617158.71UniProt (Q5SHQ1)
Pfam (PF00253)
UniProt (by SIFTS) (P0DOY6)
Thermus thermophilus HB8
19T
(6I)
30S ribosomal protein S15polymer8910578.41UniProt (Q5SJ76)
Pfam (PF00312)
Thermus thermophilus HB8
20U
(7I)
30S ribosomal protein S16polymer8810410.01UniProt (Q5SJH3)
Pfam (PF00886)
Thermus thermophilus HB8
21V
(8I)
30S ribosomal protein S17polymer10512325.71UniProt (Q5SHP7)
Pfam (PF00366)
UniProt (by SIFTS) (P0DOY7)
Thermus thermophilus HB8
22W
(9I)
30S ribosomal protein S18polymer8810258.31UniProt (Q5SLQ0)
Pfam (PF01084)
Thermus thermophilus HB8
23X
(AI)
30S ribosomal protein S19polymer9310605.51UniProt (Q5SHP2)
Pfam (PF00203)
Thermus thermophilus HB8
24Y
(BI)
30S ribosomal protein S20polymer10611736.11UniProt (P80380)
Pfam (PF01649)
Thermus thermophilus HB8
25Z
(1F)
30S ribosomal protein Thxpolymer273350.01UniProt (Q5SIH3)
Pfam (PF17070)
Thermus thermophilus HB8S31
26AA
(1K)
tRNA-Phepolymer7624633.91Escherichia coli K-12
27FA, GA
(1J, 16)
5S ribosomal RNApolymer12239540.62GenBank (55771382)Thermus thermophilus HB8
28HA
(11)
50S ribosomal protein L2polymer27630532.61UniProt (P60405)
Pfam (PF00181)
Pfam (PF03947)
Thermus thermophilus HB8
29IA
(21)
50S ribosomal protein L3polymer20622450.21UniProt (Q5SHN8)
Pfam (PF00297)
Thermus thermophilus HB8
30JA
(31)
50S ribosomal protein L4polymer21023271.91UniProt (Q5SHN9)
Pfam (PF00573)
Thermus thermophilus HB8L1e
31KA
(41)
50S ribosomal protein L5polymer18221061.61UniProt (Q5SHQ0)
Pfam (PF00281)
Pfam (PF00673)
Thermus thermophilus HB8
32LA
(51)
50S ribosomal protein L6polymer18019568.91UniProt (Q5SHQ3)
Pfam (PF00347)
UniProt (by SIFTS) (P0DOY8)
Thermus thermophilus HB8
33MA
(61)
50S ribosomal protein L9polymer14816422.21UniProt (Q5SLQ1)
Pfam (PF01281)
Pfam (PF03948)
Thermus thermophilus HB8
34NA
(58)
50S ribosomal protein L13polymer14015927.91UniProt (P60488)
Pfam (PF00572)
Thermus thermophilus HB8
35OA
(68)
50S ribosomal protein L14polymer12213323.61UniProt (Q5SHP8)
Pfam (PF00238)
Thermus thermophilus HB8
36PA
(78)
50S ribosomal protein L15polymer15016319.11UniProt (Q5SHQ7)
Pfam (PF00828)
Thermus thermophilus HB8
37QA
(88)
50S ribosomal protein L16polymer14115993.91UniProt (P60489)
Pfam (PF00252)
Thermus thermophilus HB8
38RA
(98)
50S ribosomal protein L17polymer11813750.11UniProt (Q9Z9H5)
Pfam (PF01196)
Thermus thermophilus HB8
39SA
(A8)
50S ribosomal protein L18polymer11212639.81UniProt (Q5SHQ4)
Pfam (PF00861)
Thermus thermophilus HB8TL24
40TA
(B8)
50S ribosomal protein L19polymer14617188.81UniProt (P60490)
Pfam (PF01245)
Thermus thermophilus HB8
41UA
(C8)
50S ribosomal protein L20polymer11813779.31UniProt (P60491)
Pfam (PF00453)
Thermus thermophilus HB8
42VA
(D8)
50S ribosomal protein L21polymer10111069.21UniProt (P60492)
Pfam (PF00829)
Thermus thermophilus HB8
43WA
(E8)
50S ribosomal protein L22polymer11312808.11UniProt (Q5SHP3)
Pfam (PF00237)
Thermus thermophilus HB8
44XA
(F8)
50S ribosomal protein L23polymer9610759.81UniProt (Q5SHP0)
Pfam (PF00276)
Thermus thermophilus HB8
45YA
(G8)
50S ribosomal protein L24polymer11012085.61UniProt (Q5SHP9)
Pfam (PF00467)
Pfam (PF17136)
Thermus thermophilus HB8
46ZA
(H8)
50S ribosomal protein L25polymer20623238.61UniProt (Q5SHZ1)
Pfam (PF01386)
Pfam (PF14693)
Thermus thermophilus HB8TL5
47AB
(I8)
50S ribosomal protein L27polymer859557.11UniProt (P60493)
Pfam (PF01016)
Thermus thermophilus HB8
48BB
(J8)
50S ribosomal protein L28polymer9811004.21UniProt (P60494)
Pfam (PF00830)
Thermus thermophilus HB8
49CB
(K8)
50S ribosomal protein L29polymer728670.31UniProt (Q5SHP6)
Pfam (PF00831)
Thermus thermophilus HB8
50DB
(L8)
50S ribosomal protein L30polymer606799.11UniProt (Q5SHQ6)
Pfam (PF00327)
Thermus thermophilus HB8
51EB
(M8)
50S ribosomal protein L31polymer718300.51UniProt (Q5SJE1)
Pfam (PF01197)
Thermus thermophilus HB8
52FB
(N8)
50S ribosomal protein L32polymer606722.11UniProt (P80339)
Pfam (PF01783)
Thermus thermophilus HB8
53GB
(O8)
50S ribosomal protein L33polymer546632.91UniProt (P35871)
Pfam (PF00471)
Thermus thermophilus HB8
54HB
(P8)
50S ribosomal protein L34polymer496132.41UniProt (P80340)
Pfam (PF00468)
Thermus thermophilus HB8
55IB
(Q8)
50S ribosomal protein L35polymer657506.21UniProt (Q5SKU1)
Pfam (PF01632)
Thermus thermophilus HB8
56AAA, ABA, AC, ACA, AD...
(1H, 13, 14, 41, 1G...)
MAGNESIUM IONnon-polymer24.31259Chemie (MG)
57AY, CYA, DYA, FUA, TX...
(5I, 1G, 32, G8, 14...)
ZINC IONnon-polymer65.46Chemie (ZN)
58AZA, BZA, CZA, DZA, EYA...
(31, 58, 78, 98, 13...)
waterwater18.02532Chemie (HOH)
Sequence modifications
13, 1G: 0 - 1544 (GenBank: 155076)
14, 1H: 1 - 2907 (GenBank: 48268)
PDBExternal DatabaseDetails
U 161-insertion
G 493-insertion
G 1228-insertion
4I: 1 - 126 (UniProt: P80377)
PDBExternal DatabaseDetails
Ala 119Gly 119conflict
I8: 1 - 85 (UniProt: P60493)
PDBExternal DatabaseDetails
Ala 6Gly 6conflict
Ala 8Gly 8conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains65
Total formula weight3895331.6
Non-Polymers*Number of molecules1265
Total formula weight30992.4
All*Total formula weight3926324.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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