4WPL

Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with uracil, Form I

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Uracil-DNA glycosylase	polymer	238	25813.5	1	UniProt (P9WFQ9) Pfam (PF03167)	Mycobacterium tuberculosis H37Rv	UDG
2	B (A)	URACIL	non-polymer		112.1	1	Chemie (URA)
3	C, D, E (A)	DIMETHYL SULFOXIDE	non-polymer		78.1	3	Chemie (DMS)
4	F (A)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
5	G, H, I, J, K (A)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
6	L (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7	M (A)	water	water		18.0	241	Chemie (HOH)

Sequence modifications

A: 1 - 227 (UniProt: P9WFQ9)

PDB	External Database	Details
Met -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Gly -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	25813.5
Non-Polymers*	Number of molecules	11
	Total formula weight	901.5
All*	Total formula weight	26715.0

*Water molecules are not included.