4WPI

Crystal structure of USP7 ubiquitin-like domains in extended conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Ubiquitin carboxyl-terminal hydrolase 7	polymer	375	44495.1	2	UniProt (Q93009) Pfam (PF12436) In PDB	Homo sapiens (Human)	Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7
2	C, D	ICP0	polymer	11	1315.6	2	UniProt (by SIFTS) (P08393) In PDB	Herpes simplex virus (type 1 / strain 17)
3	A, B	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)

Sequence modifications

A, B: 535 - 888 (UniProt: Q93009)

PDB	External Database	Details
Mse 514	-	initiating methionine
Gly 515	-	expression tag
Ser 516	-	expression tag
Ser 517	-	expression tag
His 518	-	expression tag
His 519	-	expression tag
His 520	-	expression tag
His 521	-	expression tag
His 522	-	expression tag
His 523	-	expression tag
Ser 524	-	expression tag
Ser 525	-	expression tag
Gly 526	-	expression tag
Arg 527	-	expression tag
Glu 528	-	expression tag
Asn 529	-	expression tag
Leu 530	-	expression tag
Tyr 531	-	expression tag
Phe 532	-	expression tag
Gln 533	-	expression tag
Gly 534	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	91621.3
Non-Polymers*	Number of molecules	3
	Total formula weight	106.4
All*	Total formula weight	91727.7

*Water molecules are not included.