4WP0
Crystal structure of human kynurenine aminotransferase-I with a C-terminal V5-hexahistidine tag
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Kynurenine--oxoglutarate transaminase 1 | polymer | 472 | 53822.4 | 4 | UniProt (Q16773) Pfam (PF00155) | Homo sapiens (Human) | Cysteine-S-conjugate beta-lyase,Glutamine transaminase K,GTK,Glutamine--phenylpyruvate transaminase,Kynurenine aminotransferase I,KATI,Kynurenine--oxoglutarate transaminase I |
| 2 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 422 (UniProt: Q16773)
| PDB | External Database | Details |
|---|---|---|
| Glu 423 | - | expression tag |
| Asn 424 | - | expression tag |
| Leu 425 | - | expression tag |
| Tyr 426 | - | expression tag |
| Phe 427 | - | expression tag |
| Gln 428 | - | expression tag |
| Gly 429 | - | expression tag |
| Lys 430 | - | expression tag |
| Gly 431 | - | expression tag |
| Gly 432 | - | expression tag |
| Arg 433 | - | expression tag |
| Ala 434 | - | expression tag |
| Asp 435 | - | expression tag |
| Pro 436 | - | expression tag |
| Ala 437 | - | expression tag |
| Phe 438 | - | expression tag |
| Leu 439 | - | expression tag |
| Tyr 440 | - | expression tag |
| Lys 441 | - | expression tag |
| Val 442 | - | expression tag |
| Val 443 | - | expression tag |
| Arg 444 | - | expression tag |
| Met 445 | - | expression tag |
| Asn 446 | - | expression tag |
| Glu 447 | - | expression tag |
| Asp 448 | - | expression tag |
| Leu 449 | - | expression tag |
| Gly 450 | - | expression tag |
| Lys 451 | - | expression tag |
| Pro 452 | - | expression tag |
| Ile 453 | - | expression tag |
| Pro 454 | - | expression tag |
| Asn 455 | - | expression tag |
| Pro 456 | - | expression tag |
| Leu 457 | - | expression tag |
| Leu 458 | - | expression tag |
| Gly 459 | - | expression tag |
| Leu 460 | - | expression tag |
| Asp 461 | - | expression tag |
| Ser 462 | - | expression tag |
| Thr 463 | - | expression tag |
| Arg 464 | - | expression tag |
| Thr 465 | - | expression tag |
| Gly 466 | - | expression tag |
| His 467 | - | expression tag |
| His 468 | - | expression tag |
| His 469 | - | expression tag |
| His 470 | - | expression tag |
| His 471 | - | expression tag |
| His 472 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 215289.4 | |
| All* | Total formula weight | 215289.4 |
