4WP0

Crystal structure of human kynurenine aminotransferase-I with a C-terminal V5-hexahistidine tag

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0008483	molecular_function	transaminase activity
A	0009058	biological_process	biosynthetic process
A	0009617	biological_process	response to bacterium
A	0016212	molecular_function	kynurenine-oxoglutarate transaminase activity
A	0016740	molecular_function	transferase activity
A	0016829	molecular_function	lyase activity
A	0030170	molecular_function	pyridoxal phosphate binding
A	0042803	molecular_function	protein homodimerization activity
A	0047316	molecular_function	glutamine-phenylpyruvate transaminase activity
A	0047804	molecular_function	cysteine-S-conjugate beta-lyase activity
A	0070189	biological_process	kynurenine metabolic process
A	0097053	biological_process	L-kynurenine catabolic process
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0008483	molecular_function	transaminase activity
B	0009058	biological_process	biosynthetic process
B	0009617	biological_process	response to bacterium
B	0016212	molecular_function	kynurenine-oxoglutarate transaminase activity
B	0016740	molecular_function	transferase activity
B	0016829	molecular_function	lyase activity
B	0030170	molecular_function	pyridoxal phosphate binding
B	0042803	molecular_function	protein homodimerization activity
B	0047316	molecular_function	glutamine-phenylpyruvate transaminase activity
B	0047804	molecular_function	cysteine-S-conjugate beta-lyase activity
B	0070189	biological_process	kynurenine metabolic process
B	0097053	biological_process	L-kynurenine catabolic process
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0008483	molecular_function	transaminase activity
C	0009058	biological_process	biosynthetic process
C	0009617	biological_process	response to bacterium
C	0016212	molecular_function	kynurenine-oxoglutarate transaminase activity
C	0016740	molecular_function	transferase activity
C	0016829	molecular_function	lyase activity
C	0030170	molecular_function	pyridoxal phosphate binding
C	0042803	molecular_function	protein homodimerization activity
C	0047316	molecular_function	glutamine-phenylpyruvate transaminase activity
C	0047804	molecular_function	cysteine-S-conjugate beta-lyase activity
C	0070189	biological_process	kynurenine metabolic process
C	0097053	biological_process	L-kynurenine catabolic process
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0008483	molecular_function	transaminase activity
D	0009058	biological_process	biosynthetic process
D	0009617	biological_process	response to bacterium
D	0016212	molecular_function	kynurenine-oxoglutarate transaminase activity
D	0016740	molecular_function	transferase activity
D	0016829	molecular_function	lyase activity
D	0030170	molecular_function	pyridoxal phosphate binding
D	0042803	molecular_function	protein homodimerization activity
D	0047316	molecular_function	glutamine-phenylpyruvate transaminase activity
D	0047804	molecular_function	cysteine-S-conjugate beta-lyase activity
D	0070189	biological_process	kynurenine metabolic process
D	0097053	biological_process	L-kynurenine catabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15364907","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1W7M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"15364907","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1W7L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W7M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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