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4WLS

Crystal structure of the metal-free (repressor) form of E. Coli CUER, a copper efflux regulator, bound to COPA promoter DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
HTH-type transcriptional regulator CueRpolymer12814596.82UniProt (P0A9G4)
Pfam (PF00376)
Pfam (PF09278)
Escherichia coli DH5[alpha]Copper efflux regulator,Copper export regulator
2C
(X)
COPA PROMOTER DNA NON-TEMPLATE STRANDpolymer267945.11synthetic construct
3D
(Y)
COPA PROMOTER DNA TEMPLATE STRANDpolymer268030.21synthetic construct
4E
(U)
COPA PROMOTER DNA TEMPLATE STRAND (ALTERNATE CONFORMATION)polymer268039.21synthetic construct
5F
(V)
COPA PROMOTER DNA NON-TEMPLATE STRAND (ALTERNATE CONFORMATION)polymer267936.11synthetic construct
6G, H, I, J
(A, B, X, V)
waterwater18.023Chemie (HOH)
Sequence modifications
A, B: 1 - 128 (UniProt: P0A9G4)
PDBExternal DatabaseDetails
Ser 112Cys 112engineered mutation
Ser 120Cys 120engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight61144.3
All*Total formula weight61144.3
*Water molecules are not included.

246333

PDB entries from 2025-12-17

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