4WH7
Structure of the CDC25B Phosphatase Catalytic Domain with Bound Ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | M-phase inducer phosphatase 2 | polymer | 183 | 21449.4 | 1 | UniProt (P30305) Pfam (PF00581) In PDB | Homo sapiens (Human) | Dual specificity phosphatase Cdc25B |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 3 | A | 2-fluoro-4-hydroxybenzonitrile | non-polymer | 137.1 | 1 | Chemie (8H8) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 287 | Chemie (HOH) |
Sequence modifications
A: 372 - 551 (UniProt: P30305)
| PDB | External Database | Details |
|---|---|---|
| Gly 369 | - | expression tag |
| Ser 370 | - | expression tag |
| Ser 371 | - | expression tag |
| Ser 473 | Cys 487 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21449.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 805.6 | |
| All* | Total formula weight | 22255.0 |
