4WBB
Single Turnover Autophosphorylation Cycle of the PKA RIIb Holoenzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase type II-beta regulatory subunit | polymer | 416 | 46273.9 | 1 | UniProt (P31324) Pfam (PF02197) Pfam (PF00027) | Mus musculus (Mouse) | |
| 2 | B (B) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 350 | 40737.3 | 1 | UniProt (P05132) Pfam (PF00069) | Mus musculus (Mouse) | PKA C-alpha |
| 3 | C, E (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | D (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A: 1 - 416 (UniProt: P31324)
| PDB | External Database | Details |
|---|---|---|
| Lys 230 | Arg 230 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 87011.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 507.4 | |
| All* | Total formula weight | 87518.6 |
