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4WA7

Crystal Structure of a GDP-bound Q61L Oncogenic Mutant of Human GT- Pase KRas

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AGTPase KRaspolymer17019313.81UniProt (P01116)
Pfam (PF00071)
In PDB
Homo sapiens (Human)K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2AGUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3AMAGNESIUM IONnon-polymer24.31Chemie (MG)
4waterwater18.037Chemie (HOH)
Sequence modifications
A: 1 - 169 (UniProt: P01116)
PDBExternal DatabaseDetails
Gly 0-expression tag
Leu 61Gln 61engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19313.8
Non-Polymers*Number of molecules2
Total formula weight467.5
All*Total formula weight19781.3
*Water molecules are not included.

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PDB entries from 2024-06-26

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