4W8D
Crystal structure of MST3 with a pyrrolopyrimidine inhibitor (PF-06454589).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase 24 36 kDa subunit | polymer | 290 | 32954.8 | 1 | UniProt (Q9Y6E0) Pfam (PF00069) | Homo sapiens (Human) | Mammalian STE20-like protein kinase 3 N-terminal, MST-3/N |
| 2 | B (A) | 5-(1-methyl-1H-pyrazol-4-yl)-4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidine | non-polymer | 284.3 | 1 | Chemie (3JA) | |||
| 3 | C (A) | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32954.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 284.3 | |
| All* | Total formula weight | 33239.1 |
