4W5S
Tankyrase in complex with compound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tankyrase-1 | polymer | 211 | 24169.4 | 1 | UniProt (O95271) Pfam (PF00644) | Homo sapiens (Human) | TANK1,ADP-ribosyltransferase diphtheria toxin-like 5,ARTD5,Poly [ADP-ribose] polymerase 5A,TNKS-1,TRF1-interacting ankyrin-related ADP-ribose polymerase,Tankyrase I |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | 8-(hydroxymethyl)-2-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]quinazolin-4(3H)-one | non-polymer | 332.4 | 1 | Chemie (3J1) | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (A) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A: 1105 - 1314 (UniProt: O95271)
| PDB | External Database | Details |
|---|---|---|
| Ala 1104 | - | expression tag |
| Ala 1286 | Gly 1286 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24169.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 489.9 | |
| All* | Total formula weight | 24659.3 |
