4W5S

Tankyrase in complex with compound

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	RIGAKU FR-E DW
Temperature [K]	93
Detector technology	CCD
Collection date	2010-03-26
Detector	RIGAKU SATURN 944+
Wavelength(s)	1.54
Spacegroup name	I 21 21 21
Unit cell lengths	81.010, 81.930, 82.170
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	58.020 - 2.800
R-factor	0.2004
Rwork	0.197
R-free	0.26320
RMSD bond length	0.010
RMSD bond angle	1.140
Refinement software	BUSTER (2.11.5)

Data quality characteristics

	Overall
Low resolution limit [Å]	58.020
High resolution limit [Å]	2.800
Number of reflections	7011
<I/σ(I)>	7.6
Completeness [%]	99.8
Redundancy	6.95

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	6.5	293	15% Peg 3350, PCTP Buffer pH 6.5, 100 mM MgCl2