4W5K
Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei, K237A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aspartate aminotransferase, mitochondrial | polymer | 396 | 43819.1 | 2 | UniProt (Q385Q9) Pfam (PF00155) | Trypanosoma brucei brucei | |
| 2 | C, F (A, B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
| 3 | D, G (A, B) | D-MALATE | non-polymer | 134.1 | 2 | Chemie (MLT) | |||
| 4 | E, H (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 794 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 388 (UniProt: Q385Q9)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | expression tag |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Leu 147 | Phe 147 | conflict |
| Ala 237 | Lys 237 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 87638.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 886.6 | |
| All* | Total formula weight | 88524.9 |






