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4W5K

Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei, K237A mutant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Aspartate aminotransferase, mitochondrialpolymer39643819.12UniProt (Q385Q9)
Pfam (PF00155)
Trypanosoma brucei brucei
2C, F
(A, B)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.12Chemie (PLP)
3D, G
(A, B)
D-MALATEnon-polymer134.12Chemie (MLT)
4E, H
(A, B)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
5I, J
(A, B)
waterwater18.0794Chemie (HOH)
Sequence modifications
A, B: 1 - 388 (UniProt: Q385Q9)
PDBExternal DatabaseDetails
Met -7-expression tag
Ala -6-expression tag
His -5-expression tag
His -4-expression tag
His -3-expression tag
His -2-expression tag
His -1-expression tag
His 0-expression tag
Leu 147Phe 147conflict
Ala 237Lys 237engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight87638.3
Non-Polymers*Number of molecules6
Total formula weight886.6
All*Total formula weight88524.9
*Water molecules are not included.

243531

PDB entries from 2025-10-22

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