4W50
Structure of the EphA4 LBD in complex with peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ephrin type-A receptor 4 | polymer | 179 | 20489.1 | 4 | UniProt (P54764) Pfam (PF01404) | Homo sapiens (Human) | EPH-like kinase 8,hEK8,Tyrosine-protein kinase TYRO1,Tyrosine-protein kinase receptor SEK |
| 2 | E, F, G, H (E, F, G, H) | APY peptide | polymer | 12 | 1392.6 | 4 | synthetic construct | ||
| 3 | I, M, O, Q (A, B, C, D) | 1,3-BUTANEDIOL | non-polymer | 90.1 | 4 | Chemie (BU2) | |||
| 4 | J, K, L, N, P... (A, B, C, D) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | S, T, U, V, W... (A, B, C, D, E...) | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 29 - 204 (UniProt: P54764)
| PDB | External Database | Details |
|---|---|---|
| Gly 26 | - | expression tag |
| Pro 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Ala 204 | Cys 204 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 87526.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 913.0 | |
| All* | Total formula weight | 88440.0 |
