4W2E
Crystal structure of Elongation Factor 4 (EF4/LepA) bound to the Thermus thermophilus 70S ribosome
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 23S Ribosomal RNA | polymer | 2915 | 947895.4 | 1 | Thermus thermophilus | ||
2 | B | 5S Ribosomal RNA | polymer | 122 | 39494.5 | 1 | Thermus thermophilus | ||
3 | D | 50S ribosomal protein L2 | polymer | 276 | 30532.6 | 1 | UniProt (P60405) Pfam (PF00181) Pfam (PF03947) In PDB | Thermus thermophilus | |
4 | E | 50S ribosomal protein L3 | polymer | 206 | 22450.2 | 1 | UniProt (Q5SHN8) Pfam (PF00297) In PDB | Thermus thermophilus | |
5 | F | 50S ribosomal protein L4 | polymer | 205 | 22712.2 | 1 | UniProt (Q5SHN9) Pfam (PF00573) In PDB | Thermus thermophilus | L1e |
6 | G | 50S ribosomal protein L5 | polymer | 182 | 21061.6 | 1 | UniProt (Q5SHQ0) Pfam (PF00281) Pfam (PF00673) In PDB | Thermus thermophilus | |
7 | H | 50S ribosomal protein L6 | polymer | 180 | 19568.9 | 1 | UniProt (Q5SHQ3) In PDB | Thermus thermophilus | |
8 | J | 50S ribosomal protein L10 | polymer | 173 | 18586.6 | 1 | UniProt (Q8VVE3) Pfam (PF00466) In PDB | Thermus thermophilus | |
9 | K | 50S ribosomal protein L11 | polymer | 147 | 15526.1 | 1 | UniProt (Q5SLP6) Pfam (PF03946) Pfam (PF00298) In PDB | Thermus thermophilus | |
10 | N | 50S ribosomal protein L13 | polymer | 140 | 15927.9 | 1 | UniProt (P60488) Pfam (PF00572) In PDB | Thermus thermophilus | |
11 | O | 50S ribosomal protein L14 | polymer | 122 | 13323.6 | 1 | UniProt (Q5SHP8) Pfam (PF00238) In PDB | Thermus thermophilus | |
12 | P | 50S ribosomal protein L15 | polymer | 150 | 16319.1 | 1 | UniProt (Q5SHQ7) Pfam (PF00828) In PDB | Thermus thermophilus | |
13 | Q | 50S ribosomal protein L16 | polymer | 141 | 15993.9 | 1 | UniProt (P60489) Pfam (PF00252) In PDB | Thermus thermophilus | TL24 |
14 | R | 50S ribosomal protein L17 | polymer | 118 | 13750.1 | 1 | UniProt (Q9Z9H5) Pfam (PF01196) In PDB | Thermus thermophilus | |
15 | S | 50S ribosomal protein L18 | polymer | 112 | 12639.8 | 1 | UniProt (Q5SHQ4) Pfam (PF00861) In PDB | Thermus thermophilus | |
16 | T | 50S ribosomal protein L19 | polymer | 146 | 17188.8 | 1 | UniProt (P60490) Pfam (PF01245) In PDB | Thermus thermophilus | |
17 | U | 50S ribosomal protein L20 | polymer | 118 | 13779.3 | 1 | UniProt (P60491) Pfam (PF00453) In PDB | Thermus thermophilus | |
18 | V | 50S ribosomal protein L21 | polymer | 101 | 11069.2 | 1 | UniProt (P60492) Pfam (PF00829) In PDB | Thermus thermophilus | |
19 | W | 50S ribosomal protein L22 | polymer | 113 | 12808.1 | 1 | UniProt (Q5SHP3) Pfam (PF00237) In PDB | Thermus thermophilus | |
20 | X | 50S ribosomal protein L23 | polymer | 96 | 10759.8 | 1 | UniProt (Q5SHP0) Pfam (PF00276) In PDB | Thermus thermophilus | TL5 |
21 | Y | 50S ribosomal protein L24 | polymer | 110 | 12085.6 | 1 | UniProt (Q5SHP9) Pfam (PF00467) Pfam (PF17136) In PDB | Thermus thermophilus | |
22 | Z | 50S ribosomal protein L25 | polymer | 206 | 23238.6 | 1 | UniProt (Q5SHZ1) Pfam (PF01386) Pfam (PF14693) In PDB | Thermus thermophilus | |
23 | 0 | 50S ribosomal protein L27 | polymer | 85 | 9529.1 | 1 | UniProt (P60493) Pfam (PF01016) In PDB | Thermus thermophilus | |
24 | 1 | 50S ribosomal protein L28 | polymer | 98 | 11004.2 | 1 | UniProt (P60494) Pfam (PF00830) In PDB | Thermus thermophilus | |
25 | 2 | 50S ribosomal protein L29 | polymer | 72 | 8670.3 | 1 | UniProt (Q5SHP6) Pfam (PF00831) In PDB | Thermus thermophilus | |
26 | 3 | 50S ribosomal protein L30 | polymer | 60 | 6799.1 | 1 | UniProt (Q5SHQ6) Pfam (PF00327) In PDB | Thermus thermophilus | |
27 | 4 | 50S ribosomal protein L31 | polymer | 71 | 8300.5 | 1 | UniProt (Q5SJE1) Pfam (PF01197) In PDB | Thermus thermophilus | |
28 | 5 | 50S ribosomal protein L32 | polymer | 60 | 6722.1 | 1 | UniProt (P80339) Pfam (PF01783) In PDB | Thermus thermophilus | |
29 | 6 | 50S ribosomal protein L33 | polymer | 54 | 6632.9 | 1 | UniProt (P35871) Pfam (PF00471) In PDB | Thermus thermophilus | |
30 | 7 | 50S ribosomal protein L34 | polymer | 49 | 6132.4 | 1 | UniProt (P80340) Pfam (PF00468) In PDB | Thermus thermophilus | Ribosomal protein B |
31 | 8 | 50S ribosomal protein L35 | polymer | 65 | 7506.2 | 1 | UniProt (Q5SKU1) Pfam (PF01632) In PDB | Thermus thermophilus | |
32 | 9 | 50S ribosomal protein L36 | polymer | 37 | 4435.4 | 1 | UniProt (Q5SHR2) Pfam (PF00444) In PDB | Thermus thermophilus | |
33 | x, w | E-site tRNA | polymer | 76 | 24645.9 | 2 | Escherichia coli | ||
34 | a | 16S Ribosomal RNA | polymer | 1521 | 493652.2 | 1 | Thermus thermophilus | ||
35 | b | 30S ribosomal protein S2 | polymer | 256 | 29317.7 | 1 | UniProt (P80371) Pfam (PF00318) In PDB | Thermus thermophilus | |
36 | c | 30S ribosomal protein S3 | polymer | 239 | 26751.1 | 1 | UniProt (P80372) Pfam (PF07650) Pfam (PF00189) In PDB | Thermus thermophilus | |
37 | d | 30S ribosomal protein S4 | polymer | 209 | 24373.4 | 1 | UniProt (P80373) Pfam (PF00163) Pfam (PF01479) In PDB | Thermus thermophilus | |
38 | e | 30S ribosomal protein S5 | polymer | 162 | 17583.4 | 1 | UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719) In PDB | Thermus thermophilus | |
39 | f | 30S ribosomal protein S6 | polymer | 101 | 11988.8 | 1 | UniProt (Q5SLP8) Pfam (PF01250) In PDB | Thermus thermophilus | TS9 |
40 | g | 30S ribosomal protein S7 | polymer | 156 | 18051.0 | 1 | UniProt (P17291) Pfam (PF00177) In PDB | Thermus thermophilus | |
41 | h | 30S ribosomal protein S8 | polymer | 138 | 15868.6 | 1 | UniProt (Q5SHQ2) In PDB | Thermus thermophilus | |
42 | i | 30S ribosomal protein S9 | polymer | 128 | 14410.6 | 1 | UniProt (P80374) Pfam (PF00380) In PDB | Thermus thermophilus | |
43 | j | 30S ribosomal protein S10 | polymer | 105 | 11955.0 | 1 | UniProt (Q5SHN7) Pfam (PF00338) In PDB | Thermus thermophilus | |
44 | k | 30S ribosomal protein S11 | polymer | 129 | 13737.9 | 1 | UniProt (P80376) Pfam (PF00411) In PDB | Thermus thermophilus | |
45 | l | 30S ribosomal protein S12 | polymer | 132 | 14637.4 | 1 | UniProt (Q5SHN3) Pfam (PF00164) In PDB | Thermus thermophilus | |
46 | m | 30S ribosomal protein S13 | polymer | 126 | 14338.9 | 1 | UniProt (P80377) Pfam (PF00416) In PDB | Thermus thermophilus | |
47 | n | 30S ribosomal protein S14 type Z | polymer | 61 | 7158.7 | 1 | UniProt (Q5SHQ1) In PDB | Thermus thermophilus | |
48 | o | 30S ribosomal protein S15 | polymer | 89 | 10578.4 | 1 | UniProt (Q5SJ76) Pfam (PF00312) In PDB | Thermus thermophilus | |
49 | p | 30S ribosomal protein S16 | polymer | 88 | 10410.0 | 1 | UniProt (Q5SJH3) Pfam (PF00886) In PDB | Thermus thermophilus | |
50 | q | 30S ribosomal protein S17 | polymer | 105 | 12325.7 | 1 | UniProt (Q5SHP7) In PDB | Thermus thermophilus | |
51 | r | 30S ribosomal protein S18 | polymer | 88 | 10258.3 | 1 | UniProt (Q5SLQ0) Pfam (PF01084) In PDB | Thermus thermophilus | |
52 | s | 30S ribosomal protein S19 | polymer | 93 | 10605.5 | 1 | UniProt (Q5SHP2) Pfam (PF00203) In PDB | Thermus thermophilus | |
53 | t | 30S ribosomal protein S20 | polymer | 106 | 11736.1 | 1 | UniProt (P80380) Pfam (PF01649) In PDB | Thermus thermophilus | |
54 | u | 30S ribosomal protein Thx | polymer | 27 | 3350.0 | 1 | UniProt (Q5SIH3) Pfam (PF17070) In PDB | Thermus thermophilus | S31 |
55 | v | mRNA | polymer | 18 | 5859.6 | 1 | synthetic construct | ||
56 | y | 50S ribosomal protein L9, Elongation factor 4 | polymer | 679 | 75318.6 | 1 | UniProt (Q5SLQ1) UniProt (Q5SKA7) Pfam (PF01281) Pfam (PF00009) Pfam (PF03144) Pfam (PF00679) Pfam (PF06421) In PDB | Thermus thermophilus | EF-4, Ribosomal back-translocase LepA |
57 | B, O, A, a, w... | MAGNESIUM ION | non-polymer | 24.3 | 906 | Chemie (MG) | |||
58 | 5, 6, 9, Y, 4... | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
59 | d | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
60 | w | PHENYLALANINE | non-polymer | 165.2 | 1 | Chemie (PHE) | |||
61 | y | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
62 | water | water | 18.0 | 969 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 57 |
Total formula weight | 2316002.6 | |
Non-Polymers* | Number of molecules | 915 |
Total formula weight | 23372.8 | |
All* | Total formula weight | 2339375.4 |