4W2E
Crystal structure of Elongation Factor 4 (EF4/LepA) bound to the Thermus thermophilus 70S ribosome
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 23S Ribosomal RNA | polymer | 2915 | 947895.4 | 1 | Thermus thermophilus | ||
| 2 | B (B) | 5S Ribosomal RNA | polymer | 122 | 39494.5 | 1 | Thermus thermophilus | ||
| 3 | C (D) | 50S ribosomal protein L2 | polymer | 276 | 30532.6 | 1 | UniProt (P60405) Pfam (PF00181) Pfam (PF03947) | Thermus thermophilus | |
| 4 | D (E) | 50S ribosomal protein L3 | polymer | 206 | 22450.2 | 1 | UniProt (Q5SHN8) Pfam (PF00297) | Thermus thermophilus | |
| 5 | E (F) | 50S ribosomal protein L4 | polymer | 205 | 22712.2 | 1 | UniProt (Q5SHN9) Pfam (PF00573) | Thermus thermophilus | L1e |
| 6 | F (G) | 50S ribosomal protein L5 | polymer | 182 | 21061.6 | 1 | UniProt (Q5SHQ0) Pfam (PF00281) Pfam (PF00673) | Thermus thermophilus | |
| 7 | G (H) | 50S ribosomal protein L6 | polymer | 180 | 19568.9 | 1 | UniProt (Q5SHQ3) | Thermus thermophilus | |
| 8 | H (J) | 50S ribosomal protein L10 | polymer | 173 | 18586.6 | 1 | UniProt (Q8VVE3) Pfam (PF00466) | Thermus thermophilus | |
| 9 | I (K) | 50S ribosomal protein L11 | polymer | 147 | 15526.1 | 1 | UniProt (Q5SLP6) Pfam (PF03946) Pfam (PF00298) | Thermus thermophilus | |
| 10 | J (N) | 50S ribosomal protein L13 | polymer | 140 | 15927.9 | 1 | UniProt (P60488) Pfam (PF00572) | Thermus thermophilus | |
| 11 | K (O) | 50S ribosomal protein L14 | polymer | 122 | 13323.6 | 1 | UniProt (Q5SHP8) Pfam (PF00238) | Thermus thermophilus | |
| 12 | L (P) | 50S ribosomal protein L15 | polymer | 150 | 16319.1 | 1 | UniProt (Q5SHQ7) Pfam (PF00828) | Thermus thermophilus | |
| 13 | M (Q) | 50S ribosomal protein L16 | polymer | 141 | 15993.9 | 1 | UniProt (P60489) Pfam (PF00252) | Thermus thermophilus | TL24 |
| 14 | N (R) | 50S ribosomal protein L17 | polymer | 118 | 13750.1 | 1 | UniProt (Q9Z9H5) Pfam (PF01196) | Thermus thermophilus | |
| 15 | O (S) | 50S ribosomal protein L18 | polymer | 112 | 12639.8 | 1 | UniProt (Q5SHQ4) Pfam (PF00861) | Thermus thermophilus | |
| 16 | P (T) | 50S ribosomal protein L19 | polymer | 146 | 17188.8 | 1 | UniProt (P60490) Pfam (PF01245) | Thermus thermophilus | |
| 17 | Q (U) | 50S ribosomal protein L20 | polymer | 118 | 13779.3 | 1 | UniProt (P60491) Pfam (PF00453) | Thermus thermophilus | |
| 18 | R (V) | 50S ribosomal protein L21 | polymer | 101 | 11069.2 | 1 | UniProt (P60492) Pfam (PF00829) | Thermus thermophilus | |
| 19 | S (W) | 50S ribosomal protein L22 | polymer | 113 | 12808.1 | 1 | UniProt (Q5SHP3) Pfam (PF00237) | Thermus thermophilus | |
| 20 | T (X) | 50S ribosomal protein L23 | polymer | 96 | 10759.8 | 1 | UniProt (Q5SHP0) Pfam (PF00276) | Thermus thermophilus | TL5 |
| 21 | U (Y) | 50S ribosomal protein L24 | polymer | 110 | 12085.6 | 1 | UniProt (Q5SHP9) Pfam (PF00467) Pfam (PF17136) | Thermus thermophilus | |
| 22 | V (Z) | 50S ribosomal protein L25 | polymer | 206 | 23238.6 | 1 | UniProt (Q5SHZ1) Pfam (PF01386) Pfam (PF14693) | Thermus thermophilus | |
| 23 | W (0) | 50S ribosomal protein L27 | polymer | 85 | 9529.1 | 1 | UniProt (P60493) Pfam (PF01016) | Thermus thermophilus | |
| 24 | X (1) | 50S ribosomal protein L28 | polymer | 98 | 11004.2 | 1 | UniProt (P60494) Pfam (PF00830) | Thermus thermophilus | |
| 25 | Y (2) | 50S ribosomal protein L29 | polymer | 72 | 8670.3 | 1 | UniProt (Q5SHP6) Pfam (PF00831) | Thermus thermophilus | |
| 26 | Z (3) | 50S ribosomal protein L30 | polymer | 60 | 6799.1 | 1 | UniProt (Q5SHQ6) Pfam (PF00327) | Thermus thermophilus | |
| 27 | AA (4) | 50S ribosomal protein L31 | polymer | 71 | 8300.5 | 1 | UniProt (Q5SJE1) Pfam (PF01197) | Thermus thermophilus | |
| 28 | BA (5) | 50S ribosomal protein L32 | polymer | 60 | 6722.1 | 1 | UniProt (P80339) Pfam (PF01783) | Thermus thermophilus | |
| 29 | CA (6) | 50S ribosomal protein L33 | polymer | 54 | 6632.9 | 1 | UniProt (P35871) Pfam (PF00471) | Thermus thermophilus | |
| 30 | DA (7) | 50S ribosomal protein L34 | polymer | 49 | 6132.4 | 1 | UniProt (P80340) Pfam (PF00468) | Thermus thermophilus | Ribosomal protein B |
| 31 | EA (8) | 50S ribosomal protein L35 | polymer | 65 | 7506.2 | 1 | UniProt (Q5SKU1) Pfam (PF01632) | Thermus thermophilus | |
| 32 | FA (9) | 50S ribosomal protein L36 | polymer | 37 | 4435.4 | 1 | UniProt (Q5SHR2) Pfam (PF00444) | Thermus thermophilus | |
| 33 | CB, GA (x, w) | E-site tRNA | polymer | 76 | 24645.9 | 2 | Escherichia coli | ||
| 34 | HA (a) | 16S Ribosomal RNA | polymer | 1521 | 493652.2 | 1 | Thermus thermophilus | ||
| 35 | IA (b) | 30S ribosomal protein S2 | polymer | 256 | 29317.7 | 1 | UniProt (P80371) Pfam (PF00318) | Thermus thermophilus | |
| 36 | JA (c) | 30S ribosomal protein S3 | polymer | 239 | 26751.1 | 1 | UniProt (P80372) Pfam (PF07650) Pfam (PF00189) | Thermus thermophilus | |
| 37 | KA (d) | 30S ribosomal protein S4 | polymer | 209 | 24373.4 | 1 | UniProt (P80373) Pfam (PF00163) Pfam (PF01479) | Thermus thermophilus | |
| 38 | LA (e) | 30S ribosomal protein S5 | polymer | 162 | 17583.4 | 1 | UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719) | Thermus thermophilus | |
| 39 | MA (f) | 30S ribosomal protein S6 | polymer | 101 | 11988.8 | 1 | UniProt (Q5SLP8) Pfam (PF01250) | Thermus thermophilus | TS9 |
| 40 | NA (g) | 30S ribosomal protein S7 | polymer | 156 | 18051.0 | 1 | UniProt (P17291) Pfam (PF00177) | Thermus thermophilus | |
| 41 | OA (h) | 30S ribosomal protein S8 | polymer | 138 | 15868.6 | 1 | UniProt (Q5SHQ2) | Thermus thermophilus | |
| 42 | PA (i) | 30S ribosomal protein S9 | polymer | 128 | 14410.6 | 1 | UniProt (P80374) Pfam (PF00380) | Thermus thermophilus | |
| 43 | QA (j) | 30S ribosomal protein S10 | polymer | 105 | 11955.0 | 1 | UniProt (Q5SHN7) Pfam (PF00338) | Thermus thermophilus | |
| 44 | RA (k) | 30S ribosomal protein S11 | polymer | 129 | 13737.9 | 1 | UniProt (P80376) Pfam (PF00411) | Thermus thermophilus | |
| 45 | SA (l) | 30S ribosomal protein S12 | polymer | 132 | 14637.4 | 1 | UniProt (Q5SHN3) Pfam (PF00164) | Thermus thermophilus | |
| 46 | TA (m) | 30S ribosomal protein S13 | polymer | 126 | 14338.9 | 1 | UniProt (P80377) Pfam (PF00416) | Thermus thermophilus | |
| 47 | UA (n) | 30S ribosomal protein S14 type Z | polymer | 61 | 7158.7 | 1 | UniProt (Q5SHQ1) | Thermus thermophilus | |
| 48 | VA (o) | 30S ribosomal protein S15 | polymer | 89 | 10578.4 | 1 | UniProt (Q5SJ76) Pfam (PF00312) | Thermus thermophilus | |
| 49 | WA (p) | 30S ribosomal protein S16 | polymer | 88 | 10410.0 | 1 | UniProt (Q5SJH3) Pfam (PF00886) | Thermus thermophilus | |
| 50 | XA (q) | 30S ribosomal protein S17 | polymer | 105 | 12325.7 | 1 | UniProt (Q5SHP7) | Thermus thermophilus | |
| 51 | YA (r) | 30S ribosomal protein S18 | polymer | 88 | 10258.3 | 1 | UniProt (Q5SLQ0) Pfam (PF01084) | Thermus thermophilus | |
| 52 | ZA (s) | 30S ribosomal protein S19 | polymer | 93 | 10605.5 | 1 | UniProt (Q5SHP2) Pfam (PF00203) | Thermus thermophilus | |
| 53 | AB (t) | 30S ribosomal protein S20 | polymer | 106 | 11736.1 | 1 | UniProt (P80380) Pfam (PF01649) | Thermus thermophilus | |
| 54 | BB (u) | 30S ribosomal protein Thx | polymer | 27 | 3350.0 | 1 | UniProt (Q5SIH3) Pfam (PF17070) | Thermus thermophilus | S31 |
| 55 | DB (v) | mRNA | polymer | 18 | 5859.6 | 1 | synthetic construct | ||
| 56 | EB (y) | 50S ribosomal protein L9, Elongation factor 4 | polymer | 679 | 75318.6 | 1 | UniProt (Q5SLQ1) UniProt (Q5SKA7) Pfam (PF01281) Pfam (PF00009) Pfam (PF03144) Pfam (PF00679) Pfam (PF06421) | Thermus thermophilus | EF-4, Ribosomal back-translocase LepA |
| 57 | AAA, ABA, AC, AD, ADA... (B, O, A, a, w...) | MAGNESIUM ION | non-polymer | 24.3 | 906 | Chemie (MG) | |||
| 58 | ACA, CCA, ICA, TBA, YBA... (5, 6, 9, Y, 4...) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 59 | RJA (d) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 60 | FKA (w) | PHENYLALANINE | non-polymer | 165.2 | 1 | Chemie (PHE) | |||
| 61 | JKA (y) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 62 | ALA, BLA, CLA, DLA, ELA... (Y, 0, 1, 3, 5...) | water | water | 18.0 | 969 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 57 |
| Total formula weight | 2316002.6 | |
| Non-Polymers* | Number of molecules | 915 |
| Total formula weight | 23372.8 | |
| All* | Total formula weight | 2339375.4 |
