4V8O
Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AA) | 16S RRNA | polymer | 1522 | 493958.3 | 1 | GenBank (55979969) | THERMUS THERMOPHILUS | |
| 2 | B (AB) | 30S RIBOSOMAL PROTEIN S2 | polymer | 256 | 29317.7 | 1 | UniProt (P80371) Pfam (PF00318) | THERMUS THERMOPHILUS | |
| 3 | C (AC) | 30S RIBOSOMAL PROTEIN S3 | polymer | 239 | 26751.1 | 1 | UniProt (P80372) Pfam (PF07650) Pfam (PF00189) | THERMUS THERMOPHILUS | |
| 4 | D (AD) | 30S RIBOSOMAL PROTEIN S4 | polymer | 209 | 24373.4 | 1 | UniProt (P80373) Pfam (PF00163) Pfam (PF01479) | THERMUS THERMOPHILUS | |
| 5 | E (AE) | 30S RIBOSOMAL PROTEIN S5 | polymer | 162 | 17583.4 | 1 | UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719) | THERMUS THERMOPHILUS | |
| 6 | F (AF) | 30S RIBOSOMAL PROTEIN S6 | polymer | 101 | 11988.8 | 1 | UniProt (Q5SLP8) Pfam (PF01250) | THERMUS THERMOPHILUS | |
| 7 | G (AG) | 30S RIBOSOMAL PROTEIN S7 | polymer | 156 | 18051.0 | 1 | UniProt (P17291) Pfam (PF00177) | THERMUS THERMOPHILUS | |
| 8 | H (AH) | 30S RIBOSOMAL PROTEIN S8 | polymer | 138 | 15868.6 | 1 | UniProt (Q5SHQ2) Pfam (PF00410) UniProt (by SIFTS) (P0DOY9) | THERMUS THERMOPHILUS | |
| 9 | I (AI) | 30S RIBOSOMAL PROTEIN S9 | polymer | 128 | 14429.7 | 1 | UniProt (P80374) Pfam (PF00380) | THERMUS THERMOPHILUS | |
| 10 | J (AJ) | 30S RIBOSOMAL PROTEIN S10 | polymer | 105 | 11955.0 | 1 | UniProt (Q5SHN7) Pfam (PF00338) | THERMUS THERMOPHILUS | |
| 11 | K (AK) | 30S RIBOSOMAL PROTEIN S11 | polymer | 129 | 13737.9 | 1 | UniProt (P80376) Pfam (PF00411) | THERMUS THERMOPHILUS | |
| 12 | L (AL) | 30S RIBOSOMAL PROTEIN S12 | polymer | 135 | 14920.8 | 1 | UniProt (Q5SHN3) Pfam (PF00164) | THERMUS THERMOPHILUS | |
| 13 | M (AM) | 30S RIBOSOMAL PROTEIN S13 | polymer | 126 | 14338.9 | 1 | UniProt (P80377) Pfam (PF00416) | THERMUS THERMOPHILUS | |
| 14 | N (AN) | 30S RIBOSOMAL PROTEIN S14 TYPE Z | polymer | 61 | 7158.7 | 1 | UniProt (Q5SHQ1) Pfam (PF00253) UniProt (by SIFTS) (P0DOY6) | THERMUS THERMOPHILUS | |
| 15 | O (AO) | 30S RIBOSOMAL PROTEIN S15 | polymer | 89 | 10578.4 | 1 | UniProt (Q5SJ76) Pfam (PF00312) | THERMUS THERMOPHILUS | |
| 16 | P (AP) | 30S RIBOSOMAL PROTEIN S16 | polymer | 88 | 10410.0 | 1 | UniProt (Q5SJH3) Pfam (PF00886) | THERMUS THERMOPHILUS | |
| 17 | Q (AQ) | 30S RIBOSOMAL PROTEIN S17 | polymer | 105 | 12325.7 | 1 | UniProt (Q5SHP7) Pfam (PF00366) UniProt (by SIFTS) (P0DOY7) | THERMUS THERMOPHILUS | |
| 18 | R (AR) | 30S RIBOSOMAL PROTEIN S18 | polymer | 88 | 10258.3 | 1 | UniProt (Q5SLQ0) Pfam (PF01084) | THERMUS THERMOPHILUS | |
| 19 | S (AS) | 30S RIBOSOMAL PROTEIN S19 | polymer | 93 | 10605.5 | 1 | UniProt (Q5SHP2) Pfam (PF00203) | THERMUS THERMOPHILUS | |
| 20 | T (AT) | 30S RIBOSOMAL PROTEIN S20 | polymer | 106 | 11736.1 | 1 | UniProt (P80380) Pfam (PF01649) | THERMUS THERMOPHILUS | |
| 21 | U (AU) | 30S RIBOSOMAL PROTEIN THX | polymer | 27 | 3350.0 | 1 | UniProt (Q5SIH3) Pfam (PF17070) | THERMUS THERMOPHILUS | |
| 22 | V (AV) | PE HYBRID STATE TRNA FMET | polymer | 77 | 24802.8 | 1 | ESCHERICHIA COLI | ||
| 23 | W (AX) | MRNA 5'-R(*AP*AP*AP*AP*AP*AP*UP*GP*UP)-3' | polymer | 9 | 2887.8 | 1 | ESCHERICHIA COLI | ||
| 24 | X (AY) | PEPTIDE CHAIN RELEASE FACTOR 3 | polymer | 529 | 59651.9 | 1 | UniProt (B1XFI4) Pfam (PF00009) Pfam (PF22042) Pfam (PF16658) | ESCHERICHIA COLI | RELEASE FACTOR 3, RF-3 |
| 25 | Y (B0) | 50S RIBOSOMAL PROTEIN L27 | polymer | 85 | 9529.1 | 1 | UniProt (P60493) Pfam (PF01016) | THERMUS THERMOPHILUS | |
| 26 | Z (B1) | 50S RIBOSOMAL PROTEIN L28 | polymer | 98 | 11004.2 | 1 | UniProt (P60494) Pfam (PF00830) | THERMUS THERMOPHILUS | |
| 27 | AA (B2) | 50S RIBOSOMAL PROTEIN L29 | polymer | 72 | 8670.3 | 1 | UniProt (Q5SHP6) Pfam (PF00831) | THERMUS THERMOPHILUS | |
| 28 | BA (B3) | 50S RIBOSOMAL PROTEIN L30 | polymer | 60 | 6799.1 | 1 | UniProt (Q5SHQ6) Pfam (PF00327) | THERMUS THERMOPHILUS | |
| 29 | CA (B4) | 50S RIBOSOMAL PROTEIN L31 | polymer | 71 | 8300.5 | 1 | UniProt (Q5SJE1) Pfam (PF01197) | THERMUS THERMOPHILUS | |
| 30 | DA (B5) | 50S RIBOSOMAL PROTEIN L32 | polymer | 60 | 6722.1 | 1 | UniProt (P80339) Pfam (PF01783) | THERMUS THERMOPHILUS | |
| 31 | EA (B6) | 50S RIBOSOMAL PROTEIN L33 | polymer | 54 | 6632.9 | 1 | UniProt (P35871) Pfam (PF00471) | THERMUS THERMOPHILUS | |
| 32 | FA (B7) | 50S RIBOSOMAL PROTEIN L34 | polymer | 49 | 6132.4 | 1 | UniProt (P80340) Pfam (PF00468) | THERMUS THERMOPHILUS | |
| 33 | GA (B8) | 50S RIBOSOMAL PROTEIN L35 | polymer | 65 | 7506.2 | 1 | UniProt (Q5SKU1) Pfam (PF01632) | THERMUS THERMOPHILUS | |
| 34 | HA (B9) | 50S RIBOSOMAL PROTEIN L36 | polymer | 37 | 4435.4 | 1 | UniProt (Q5SHR2) Pfam (PF00444) | THERMUS THERMOPHILUS | RIBOSOMAL PROTEIN B |
| 35 | IA (BA) | 23S RIBOSOMAL RNA | polymer | 2915 | 947975.5 | 1 | GenBank (55979969) | THERMUS THERMOPHILUS | |
| 36 | JA (BB) | 5S RIBOSOMAL RNA | polymer | 122 | 39540.6 | 1 | GenBank (55979969) | THERMUS THERMOPHILUS | |
| 37 | KA (BC) | 50S RIBOSOMAL PROTEIN L1 | polymer | 229 | 24885.7 | 1 | UniProt (Q5SLP7) Pfam (PF00687) | THERMUS THERMOPHILUS | |
| 38 | LA (BD) | 50S RIBOSOMAL PROTEIN L2 | polymer | 276 | 30532.6 | 1 | UniProt (P60405) Pfam (PF00181) Pfam (PF03947) | THERMUS THERMOPHILUS | |
| 39 | MA (BE) | 50S RIBOSOMAL PROTEIN L3 | polymer | 206 | 22450.2 | 1 | UniProt (Q5SHN8) Pfam (PF00297) | THERMUS THERMOPHILUS | |
| 40 | NA (BF) | 50S RIBOSOMAL PROTEIN L4 | polymer | 210 | 23271.9 | 1 | UniProt (Q5SHN9) Pfam (PF00573) | THERMUS THERMOPHILUS | |
| 41 | OA (BG) | 50S RIBOSOMAL PROTEIN L5 | polymer | 182 | 21061.6 | 1 | UniProt (Q5SHQ0) Pfam (PF00281) Pfam (PF00673) | THERMUS THERMOPHILUS | |
| 42 | PA (BH) | 50S RIBOSOMAL PROTEIN L6 | polymer | 180 | 19568.9 | 1 | UniProt (Q5SHQ3) Pfam (PF00347) UniProt (by SIFTS) (P0DOY8) | THERMUS THERMOPHILUS | |
| 43 | QA (BJ) | 50S RIBOSOMAL PROTEIN L10 | polymer | 173 | 14769.2 | 1 | THERMUS THERMOPHILUS | ||
| 44 | RA (BK) | 50S RIBOSOMAL PROTEIN L11 | polymer | 147 | 12528.4 | 1 | THERMUS THERMOPHILUS | ||
| 45 | SA (BN) | 50S RIBOSOMAL PROTEIN L13 | polymer | 140 | 15927.9 | 1 | UniProt (P60488) Pfam (PF00572) | THERMUS THERMOPHILUS | |
| 46 | TA (BO) | 50S RIBOSOMAL PROTEIN L14 | polymer | 122 | 13323.6 | 1 | UniProt (Q5SHP8) Pfam (PF00238) | THERMUS THERMOPHILUS | |
| 47 | UA (BP) | 50S RIBOSOMAL PROTEIN L15 | polymer | 150 | 16319.1 | 1 | UniProt (Q5SHQ7) Pfam (PF00828) | THERMUS THERMOPHILUS | |
| 48 | VA (BQ) | 50S RIBOSOMAL PROTEIN L16 | polymer | 141 | 15993.9 | 1 | UniProt (P60489) Pfam (PF00252) | THERMUS THERMOPHILUS | |
| 49 | WA (BR) | 50S RIBOSOMAL PROTEIN L17 | polymer | 118 | 13750.1 | 1 | UniProt (Q9Z9H5) Pfam (PF01196) | THERMUS THERMOPHILUS | |
| 50 | XA (BS) | 50S RIBOSOMAL PROTEIN L18 | polymer | 112 | 12639.8 | 1 | UniProt (Q5SHQ4) Pfam (PF00861) | THERMUS THERMOPHILUS | TL24 |
| 51 | YA (BT) | 50S RIBOSOMAL PROTEIN L19 | polymer | 146 | 17188.8 | 1 | UniProt (P60490) Pfam (PF01245) | THERMUS THERMOPHILUS | |
| 52 | ZA (BU) | 50S RIBOSOMAL PROTEIN L20 | polymer | 118 | 13779.3 | 1 | UniProt (P60491) Pfam (PF00453) | THERMUS THERMOPHILUS | |
| 53 | AB (BV) | 50S RIBOSOMAL PROTEIN L21 | polymer | 101 | 11069.2 | 1 | UniProt (P60492) Pfam (PF00829) | THERMUS THERMOPHILUS | |
| 54 | BB (BW) | 50S RIBOSOMAL PROTEIN L22 | polymer | 113 | 12808.1 | 1 | UniProt (Q5SHP3) Pfam (PF00237) | THERMUS THERMOPHILUS | |
| 55 | CB (BX) | 50S RIBOSOMAL PROTEIN L23 | polymer | 96 | 10759.8 | 1 | UniProt (Q5SHP0) Pfam (PF00276) | THERMUS THERMOPHILUS | L*23 |
| 56 | DB (BY) | 50S RIBOSOMAL PROTEIN L24 | polymer | 110 | 12085.6 | 1 | UniProt (Q5SHP9) Pfam (PF00467) Pfam (PF17136) | THERMUS THERMOPHILUS | |
| 57 | EB (BZ) | 50S RIBOSOMAL PROTEIN L25 | polymer | 206 | 23238.6 | 1 | UniProt (Q5SHZ1) Pfam (PF01386) Pfam (PF14693) | THERMUS THERMOPHILUS | TL5 |
| 58 | FB (AY) | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 1 | Chemie (GCP) |
Sequence modifications
AI: 1 - 128 (UniProt: P80374)
AL: 5 - 135 (UniProt: Q5SHN3)
BC: 0 - 228 (UniProt: Q5SLP7)
| PDB | External Database | Details |
|---|---|---|
| Arg 58 | His 58 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Val 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Leu 4 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ile 19 | Val 20 | conflict |
| His 27 | Arg 28 | conflict |
| Met 127 | Leu 128 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 57 |
| Total formula weight | 2292240.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 521.2 | |
| All* | Total formula weight | 2292761.5 |
