4V7Y

Structure of the Thermus thermophilus 70S ribosome complexed with azithromycin.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, ZA (AA, CA)	16S rRNA	polymer	1522	493958.3	2	GenBank (AP008226.1)	Thermus thermophilus
2	AB, B (AB, CB)	30S ribosomal protein S2	polymer	256	29317.7	2	UniProt (P80371) Pfam (PF00318)	Thermus thermophilus
3	BB, C (AC, CC)	30S ribosomal protein S3	polymer	239	26751.1	2	UniProt (P80372) Pfam (PF07650) Pfam (PF00189)	Thermus thermophilus
4	CB, D (AD, CD)	30S ribosomal protein S4	polymer	209	24373.4	2	UniProt (P80373) Pfam (PF00163) Pfam (PF01479)	Thermus thermophilus
5	DB, E (AE, CE)	30S ribosomal protein S5	polymer	162	17583.4	2	UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719)	Thermus thermophilus
6	EB, F (AF, CF)	30S ribosomal protein S6	polymer	101	11988.8	2	UniProt (Q5SLP8) Pfam (PF01250)	Thermus thermophilus
7	FB, G (AG, CG)	30S ribosomal protein S7	polymer	156	18051.0	2	UniProt (P17291) Pfam (PF00177)	Thermus thermophilus
8	GB, H (AH, CH)	30S ribosomal protein S8	polymer	138	15868.6	2	UniProt (Q5SHQ2)	Thermus thermophilus
9	HB, I (AI, CI)	30S ribosomal protein S9	polymer	128	14429.7	2	UniProt (P80374) Pfam (PF00380)	Thermus thermophilus
10	IB, J (AJ, CJ)	30S ribosomal protein S10	polymer	105	11955.0	2	UniProt (Q5SHN7) Pfam (PF00338)	Thermus thermophilus
11	JB, K (AK, CK)	30S ribosomal protein S11	polymer	129	13737.9	2	UniProt (P80376) Pfam (PF00411)	Thermus thermophilus
12	KB, L (AL, CL)	30S ribosomal protein S12	polymer	135	14920.8	2	UniProt (Q5SHN3) Pfam (PF00164)	Thermus thermophilus
13	LB, M (AM, CM)	30S ribosomal protein S13	polymer	126	14338.9	2	UniProt (P80377) Pfam (PF00416)	Thermus thermophilus
14	MB, N (AN, CN)	30S ribosomal protein S14	polymer	61	7158.7	2	UniProt (Q5SHQ1)	Thermus thermophilus
15	NB, O (AO, CO)	30S ribosomal protein S15	polymer	89	10578.4	2	UniProt (Q5SJ76) Pfam (PF00312)	Thermus thermophilus
16	OB, P (AP, CP)	30S ribosomal protein S16	polymer	88	10410.0	2	UniProt (Q5SJH3) Pfam (PF00886)	Thermus thermophilus
17	PB, Q (AQ, CQ)	30S ribosomal protein S17	polymer	105	12325.7	2	UniProt (Q5SHP7)	Thermus thermophilus
18	QB, R (AR, CR)	30S ribosomal protein S18	polymer	88	10258.3	2	UniProt (Q5SLQ0) Pfam (PF01084)	Thermus thermophilus
19	RB, S (AS, CS)	30S ribosomal protein S19	polymer	93	10605.5	2	UniProt (Q5SHP2) Pfam (PF00203)	Thermus thermophilus
20	SB, T (AT, CT)	30S ribosomal protein S20	polymer	106	11736.1	2	UniProt (P80380) Pfam (PF01649)	Thermus thermophilus
21	TB, U (AU, CU)	30S ribosomal protein Thx	polymer	27	3350.0	2	UniProt (Q5SIH3) Pfam (PF17070)	Thermus thermophilus
22	UB, V (B0, D0)	50S ribosomal protein L27	polymer	85	9529.1	2	UniProt (P60493) Pfam (PF01016)	Thermus thermophilus
23	VB, W (B1, D1)	50S ribosomal protein L28	polymer	98	11004.2	2	UniProt (P60494) Pfam (PF00830)	Thermus thermophilus
24	WB, X (B2, D2)	50S ribosomal protein L29	polymer	72	8670.3	2	UniProt (Q5SHP6) Pfam (PF00831)	Thermus thermophilus
25	XB, Y (B3, D3)	50S ribosomal protein L30	polymer	60	6799.1	2	UniProt (Q5SHQ6) Pfam (PF00327)	Thermus thermophilus
26	YB, Z (B4, D4)	50S ribosomal protein L31	polymer	71	8300.5	2	UniProt (Q5SJE1) Pfam (PF01197)	Thermus thermophilus
27	AA, ZB (B5, D5)	50S ribosomal protein L32	polymer	60	6722.1	2	UniProt (P80339) Pfam (PF01783)	Thermus thermophilus
28	AC, BA (B6, D6)	50S ribosomal protein L33	polymer	54	6632.9	2	UniProt (P35871) Pfam (PF00471)	Thermus thermophilus
29	BC, CA (B7, D7)	50S ribosomal protein L34	polymer	49	6132.4	2	UniProt (P80340) Pfam (PF00468)	Thermus thermophilus
30	CC, DA (B8, D8)	50S ribosomal protein L35	polymer	65	7506.2	2	UniProt (Q5SKU1) Pfam (PF01632)	Thermus thermophilus
31	DC, EA (BA, DA)	23S ribosomal RNA	polymer	2787	906447.8	2		Thermus thermophilus
32	EC, FA (BB, DB)	5S ribosomal RNA	polymer	122	39494.5	2	GenBank (AY379549.1)	Thermus thermophilus
33	FC, GA (BD, DD)	50S ribosomal protein L2	polymer	276	30532.6	2	UniProt (P60405) Pfam (PF00181) Pfam (PF03947)	Thermus thermophilus
34	GC, HA (BE, DE)	50S ribosomal protein L3	polymer	206	22450.2	2	UniProt (Q5SHN8) Pfam (PF00297)	Thermus thermophilus
35	HC, IA (BF, DF)	50S ribosomal protein L4	polymer	210	23271.9	2	UniProt (Q5SHN9) Pfam (PF00573)	Thermus thermophilus
36	IC, JA (BG, DG)	50S ribosomal protein L5	polymer	182	21061.6	2	UniProt (Q5SHQ0) Pfam (PF00281) Pfam (PF00673)	Thermus thermophilus
37	JC, KA (BH, DH)	50S ribosomal protein L6	polymer	180	19568.9	2	UniProt (Q5SHQ3)	Thermus thermophilus
38	KC, LA (BI, DI)	50S ribosomal protein L9	polymer	148	16422.2	2	UniProt (Q5SLQ1) Pfam (PF01281) Pfam (PF03948)	Thermus thermophilus
39	LC, MA (BN, DN)	50S ribosomal protein L13	polymer	140	15927.9	2	UniProt (P60488) Pfam (PF00572)	Thermus thermophilus
40	MC, NA (BO, DO)	50S ribosomal protein L14	polymer	122	13323.6	2	UniProt (Q5SHP8) Pfam (PF00238)	Thermus thermophilus
41	NC, OA (BP, DP)	50S ribosomal protein L15	polymer	150	16319.1	2	UniProt (Q5SHQ7) Pfam (PF00828)	Thermus thermophilus
42	OC, PA (BQ, DQ)	50S ribosomal protein L16	polymer	141	15993.9	2	UniProt (P60489) Pfam (PF00252)	Thermus thermophilus
43	PC, QA (BR, DR)	50S ribosomal protein L17	polymer	118	13750.1	2	UniProt (Q9Z9H5) Pfam (PF01196)	Thermus thermophilus
44	QC, RA (BS, DS)	50S ribosomal protein L18	polymer	112	12639.8	2	UniProt (Q5SHQ4) Pfam (PF00861)	Thermus thermophilus
45	RC, SA (BT, DT)	50S ribosomal protein L19	polymer	146	17188.8	2	UniProt (P60490) Pfam (PF01245)	Thermus thermophilus
46	SC, TA (BU, DU)	50S ribosomal protein L20	polymer	118	13779.3	2	UniProt (P60491) Pfam (PF00453)	Thermus thermophilus
47	TC, UA (BV, DV)	50S ribosomal protein L21	polymer	101	11069.2	2	UniProt (P60492) Pfam (PF00829)	Thermus thermophilus
48	UC, VA (BW, DW)	50S ribosomal protein L22	polymer	113	12808.1	2	UniProt (Q5SHP3) Pfam (PF00237)	Thermus thermophilus
49	VC, WA (BX, DX)	50S ribosomal protein L23	polymer	96	10759.8	2	UniProt (Q5SHP0) Pfam (PF00276)	Thermus thermophilus
50	WC, XA (BY, DY)	50S ribosomal protein L24	polymer	110	12085.6	2	UniProt (Q5SHP9) Pfam (PF00467) Pfam (PF17136)	Thermus thermophilus
51	XC, YA (BZ, DZ)	50S ribosomal protein L25	polymer	206	23238.6	2	UniProt (Q5SHZ1) Pfam (PF01386) Pfam (PF14693)	Thermus thermophilus
52	AAA, ABA, ACA, AD, ADA... (DA, AA, B1, BA, BP...)	MAGNESIUM ION	non-polymer		24.3	794	Chemie (MG)
53	DV, EV, XE, YE (CD, CN, AD, AN)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
54	HHA, PS (DA, BA)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
55	IHA, QS (DA, BA)	AZITHROMYCIN	non-polymer		749.0	2	Chemie (ZIT)

Sequence modifications

AI, CI: 1 - 128 (UniProt: P80374)

PDB	External Database	Details
Arg 58	His 58	conflict

AL, CL: 1 - 135 (UniProt: Q5SHN3)

PDB	External Database	Details
Val 2	-	insertion
Ala 3	-	insertion
Leu 4	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	102
	Total formula weight	4246254.6
Non-Polymers*	Number of molecules	802
	Total formula weight	21136.0
All*	Total formula weight	4267390.6

*Water molecules are not included.