4V6G

Initiation complex of 70S ribosome with two tRNAs and mRNA.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, CB (AA, CA)	16S RRNA (E.COLI NUMBERING)	polymer	1517	492467.5	2	GenBank (M26923.1)	Thermus thermophilus
2	B, DB (AE, CE)	30S RIBOSOMAL PROTEIN S2	polymer	256	29317.7	2	UniProt (P80371) Pfam (PF00318)	Thermus thermophilus
3	C, EB (AF, CF)	30S RIBOSOMAL PROTEIN S3	polymer	239	26751.1	2	UniProt (P80372) Pfam (PF07650) Pfam (PF00189)	Thermus thermophilus
4	D, FB (AG, CG)	30S RIBOSOMAL PROTEIN S4	polymer	209	24373.4	2	UniProt (P80373) Pfam (PF00163) Pfam (PF01479)	Thermus thermophilus
5	E, GB (AH, CH)	30S RIBOSOMAL PROTEIN S5	polymer	162	17583.4	2	UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719)	Thermus thermophilus
6	F, HB (AI, CI)	30S RIBOSOMAL PROTEIN S6	polymer	101	11988.8	2	UniProt (Q5SLP8) Pfam (PF01250)	Thermus thermophilus
7	G, IB (AJ, CJ)	30S RIBOSOMAL PROTEIN S7	polymer	156	18051.0	2	UniProt (P17291) Pfam (PF00177)	Thermus thermophilus
8	H, JB (AK, CK)	30S RIBOSOMAL PROTEIN S8	polymer	138	15868.6	2	UniProt (Q5SHQ2) Pfam (PF00410) UniProt (by SIFTS) (P0DOY9)	Thermus thermophilus
9	I, KB (AL, CL)	30S RIBOSOMAL PROTEIN S9	polymer	128	14410.6	2	UniProt (P80374) Pfam (PF00380)	Thermus thermophilus
10	J, LB (AM, CM)	30S RIBOSOMAL PROTEIN S10	polymer	105	11955.0	2	UniProt (Q5SHN7) Pfam (PF00338)	Thermus thermophilus
11	K, MB (AN, CN)	30S RIBOSOMAL PROTEIN S11	polymer	129	13737.9	2	UniProt (P80376) Pfam (PF00411)	Thermus thermophilus
12	L, NB (AO, CO)	30S RIBOSOMAL PROTEIN S12	polymer	132	14637.4	2	UniProt (Q5SHN3) Pfam (PF00164)	Thermus thermophilus
13	M, OB (AP, CP)	30S RIBOSOMAL PROTEIN S13	polymer	126	14338.9	2	UniProt (P80377) Pfam (PF00416)	Thermus thermophilus
14	N, PB (AQ, CQ)	30S RIBOSOMAL PROTEIN S14	polymer	61	7158.7	2	UniProt (P24320) UniProt (Q5SHQ1) Pfam (PF00253) UniProt (by SIFTS) (P0DOY6)	Thermus thermophilus
15	O, QB (AR, CR)	30S RIBOSOMAL PROTEIN S15	polymer	89	10578.4	2	UniProt (Q5SJ76) Pfam (PF00312)	Thermus thermophilus
16	P, RB (AS, CS)	30S RIBOSOMAL PROTEIN S16	polymer	88	10410.0	2	UniProt (Q5SJH3)	Thermus thermophilus
17	Q, SB (AT, CT)	30S RIBOSOMAL PROTEIN S17	polymer	105	12325.7	2	UniProt (Q5SHP7) Pfam (PF00366) UniProt (by SIFTS) (P0DOY7)	Thermus thermophilus
18	R, TB (AU, CU)	30S RIBOSOMAL PROTEIN S18	polymer	88	10258.3	2	UniProt (Q5SLQ0) Pfam (PF01084)	Thermus thermophilus
19	S, UB (AV, CV)	30S RIBOSOMAL PROTEIN S19	polymer	93	10605.5	2	UniProt (Q5SHP2) Pfam (PF00203)	Thermus thermophilus
20	T, VB (AW, CW)	30S RIBOSOMAL PROTEIN S20	polymer	106	11736.1	2	UniProt (P80380) Pfam (PF01649)	Thermus thermophilus
21	U, WB (AX, CX)	30S RIBOSOMAL PROTEIN THX	polymer	27	3350.0	2	UniProt (Q5SIH3) Pfam (PF17070)	Thermus thermophilus
22	ED, V, W, XB, YB (AC, AD, CC, CD, CB)	TRNA FMET (UNMODIFIED BASES)	polymer	77	24801.8	5		Escherichia coli
23	X, ZB (A1, C1)	MRNA	polymer	25	8227.1	2		Synthetic construct
24	AC, Y (BA, DA)	23S ribosomal RNA	polymer	2898	942506.1	2	GenBank (AP008226.1)	Thermus thermophilus
25	BC, Z (BB, DB)	5S ribosomal RNA	polymer	122	39540.6	2	GenBank (X01554.1)	Thermus thermophilus
26	AA, CC (BD, DD)	50S ribosomal protein L2	polymer	276	30532.6	2	UniProt (P60405) Pfam (PF00181) Pfam (PF03947)	Thermus thermophilus
27	BA, DC (BE, DE)	50S ribosomal protein L3	polymer	206	22450.2	2	UniProt (Q5SHN8) Pfam (PF00297)	Thermus thermophilus
28	CA, EC (BF, DF)	50S ribosomal protein L4	polymer	210	23271.9	2	UniProt (Q5SHN9) Pfam (PF00573)	Thermus thermophilus	L1e
29	DA, FC (BG, DG)	50S ribosomal protein L5	polymer	182	21061.6	2	UniProt (Q5SHQ0) Pfam (PF00281) Pfam (PF00673)	Thermus thermophilus
30	EA, GC (BH, DH)	50S ribosomal protein L6	polymer	180	19568.9	2	UniProt (Q5SHQ3) Pfam (PF00347) UniProt (by SIFTS) (P0DOY8)	Thermus thermophilus
31	FA, HC (BK, DK)	50S ribosomal protein L9	polymer	148	16422.2	2	UniProt (Q5SLQ1) Pfam (PF01281) Pfam (PF03948)	Thermus thermophilus
32	GA, IC (BM, DM)	50S ribosomal protein L13	polymer	140	15927.9	2	UniProt (P60488) Pfam (PF00572)	Thermus thermophilus
33	HA, JC (BN, DN)	50S ribosomal protein L14	polymer	122	13323.6	2	UniProt (Q5SHP8) Pfam (PF00238)	Thermus thermophilus
34	IA, KC (BO, DO)	50S ribosomal protein L15	polymer	150	16319.1	2	UniProt (Q5SHQ7) Pfam (PF00828)	Thermus thermophilus
35	JA, LC (BP, DP)	50S ribosomal protein L16	polymer	141	15993.9	2	UniProt (P60489) Pfam (PF00252)	Thermus thermophilus
36	KA, MC (B0, D0)	50S ribosomal protein L17	polymer	118	13750.1	2	UniProt (Q9Z9H5) Pfam (PF01196)	Thermus thermophilus
37	LA, NC (BQ, DQ)	50S ribosomal protein L18	polymer	112	12639.8	2	UniProt (Q5SHQ4) Pfam (PF00861)	Thermus thermophilus	TL24
38	MA, OC (BR, DR)	50S ribosomal protein L19	polymer	146	17188.8	2	UniProt (P60490) Pfam (PF01245)	Thermus thermophilus
39	NA, PC (B1, D1)	50S ribosomal protein L20	polymer	118	13779.3	2	UniProt (P60491) Pfam (PF00453)	Thermus thermophilus
40	OA, QC (B2, D2)	50S ribosomal protein L21	polymer	101	11069.2	2	UniProt (P60492) Pfam (PF00829)	Thermus thermophilus
41	PA, RC (BS, DS)	50S ribosomal protein L22	polymer	113	12808.1	2	UniProt (Q5SHP3) Pfam (PF00237)	Thermus thermophilus
42	QA, SC (BT, DT)	50S ribosomal protein L23	polymer	96	10759.8	2	UniProt (Q5SHP0) Pfam (PF00276)	Thermus thermophilus
43	RA, TC (BU, DU)	50S ribosomal protein L24	polymer	110	12085.6	2	UniProt (Q5SHP9) Pfam (PF00467) Pfam (PF17136)	Thermus thermophilus
44	SA, UC (BV, DV)	50S ribosomal protein L25	polymer	206	23238.6	2	UniProt (Q5SHZ1) Pfam (PF01386) Pfam (PF14693)	Thermus thermophilus	TL5
45	TA, VC (B3, D3)	50S ribosomal protein L27	polymer	85	9529.1	2	UniProt (P60493) Pfam (PF01016)	Thermus thermophilus
46	UA, WC (BZ, DZ)	50S ribosomal protein L28	polymer	98	11004.2	2	UniProt (P60494) Pfam (PF00830)	Thermus thermophilus
47	VA, XC (BW, DW)	50S ribosomal protein L29	polymer	72	8670.3	2	UniProt (Q5SHP6) Pfam (PF00831)	Thermus thermophilus
48	WA, YC (BX, DX)	50S ribosomal protein L30	polymer	60	6799.1	2	UniProt (Q5SHQ6) Pfam (PF00327)	Thermus thermophilus
49	XA, ZC (B4, D4)	50S ribosomal protein L31	polymer	71	8300.5	2	UniProt (Q5SJE1) Pfam (PF01197)	Thermus thermophilus
50	AD, YA (B5, D5)	50S ribosomal protein L32	polymer	60	6722.1	2	UniProt (P80339) Pfam (PF01783)	Thermus thermophilus
51	BD, ZA (B6, D6)	50S ribosomal protein L33	polymer	54	6632.9	2	UniProt (P35871) Pfam (PF00471)	Thermus thermophilus
52	AB, CD (B7, D7)	50S ribosomal protein L34	polymer	49	6132.4	2	UniProt (P80340) Pfam (PF00468)	Thermus thermophilus
53	BB, DD (B8, D8)	50S ribosomal protein L35	polymer	65	7506.2	2	UniProt (Q5SKU1) Pfam (PF01632)	Thermus thermophilus
54	AAA, AAB, AAC, AAD, ABA... (BA, CA, DA, DO, D3...)	MAGNESIUM ION	non-polymer		24.3	2653	Chemie (MG)
55	CU, DU, FU, MNB, QU... (AA, AG, CQ, AQ, CG)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)

Sequence modifications

AA, CA: 3 - 1542 (GenBank: M26923.1)

PDB	External Database	Details
G 1542	U 2165	conflict

AQ, CQ: 1 - 61 (UniProt: P24320)
BA, DA: 6 - 2897 (GenBank: AP008226.1)

PDB	External Database	Details
-	U 9395	deletion
-	U 9396	deletion
-	G 9919	deletion
-	C 9920	deletion
-	G 9921	deletion
-	G 9922	deletion
-	G 9923	deletion
-	C 9924	deletion
-	C 9925	deletion
-	G 9926	deletion
-	C 9927	deletion
-	C 9931	deletion
-	G 9932	deletion
-	G 9933	deletion
-	C 9934	deletion
-	C 9935	deletion
A 654	C 9938	conflict
U 1058	G 10343	conflict
A 1080	C 10365	conflict

BB, DB: 0 - 119 (GenBank: X01554.1)

PDB	External Database	Details
A 1	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	109
	Total formula weight	4455340.2
Non-Polymers*	Number of molecules	2659
	Total formula weight	64873.6
All*	Total formula weight	4520213.8

*Water molecules are not included.