4V6E

Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, DB (AB, CB)	30S ribosomal protein S2	polymer	241	26781.7	2	UniProt (P0A7V0) Pfam (PF00318)	Escherichia coli K-12
2	B, EB (AC, CC)	30S ribosomal protein S3	polymer	233	26031.3	2	UniProt (P0A7V3) Pfam (PF07650) Pfam (PF00189)	Escherichia coli K-12
3	C, FB (AD, CD)	30S ribosomal protein S4	polymer	206	23514.2	2	UniProt (P0A7V8) Pfam (PF00163) Pfam (PF01479)	Escherichia coli K-12
4	D, GB (AE, CE)	30S ribosomal protein S5	polymer	167	17629.4	2	UniProt (P0A7W1) Pfam (PF00333) Pfam (PF03719)	Escherichia coli K-12
5	E, HB (AF, CF)	30S ribosomal protein S6	polymer	135	15727.5	2	UniProt (P02358) Pfam (PF01250)	Escherichia coli K-12	30S ribosomal protein S6, fully modified isoform, 30S ribosomal protein S6, non-modified isoform
6	F, IB (AG, CG)	30S ribosomal protein S7	polymer	179	20055.2	2	UniProt (P02359) Pfam (PF00177)	Escherichia coli K-12
7	G, JB (AH, CH)	30S ribosomal protein S8	polymer	130	14146.6	2	UniProt (P0A7W7) Pfam (PF00410)	Escherichia coli K-12
8	H, KB (AI, CI)	30S ribosomal protein S9	polymer	130	14886.3	2	UniProt (P0A7X3) Pfam (PF00380)	Escherichia coli K-12
9	I, LB (AJ, CJ)	30S ribosomal protein S10	polymer	103	11755.6	2	UniProt (P0A7R5) Pfam (PF00338)	Escherichia coli K-12
10	J, MB (AK, CK)	30S ribosomal protein S11	polymer	129	13871.0	2	UniProt (P0A7R9) Pfam (PF00411)	Escherichia coli K-12
11	K, NB (AL, CL)	30S ribosomal protein S12	polymer	124	13768.2	2	UniProt (P0A7S3) Pfam (PF00164)	Escherichia coli K-12
12	L, OB (AM, CM)	30S ribosomal protein S13	polymer	118	13128.5	2	UniProt (P0A7S9) Pfam (PF00416)	Escherichia coli K-12
13	M, PB (AN, CN)	30S ribosomal protein S14	polymer	101	11606.6	2	UniProt (P0AG59) Pfam (PF00253)	Escherichia coli K-12
14	N, QB (AO, CO)	30S ribosomal protein S15	polymer	89	10290.8	2	UniProt (P0ADZ4) Pfam (PF00312)	Escherichia coli K-12
15	O, RB (AP, CP)	30S ribosomal protein S16	polymer	82	9207.6	2	UniProt (P0A7T3) Pfam (PF00886)	Escherichia coli K-12
16	P, SB (AQ, CQ)	30S ribosomal protein S17	polymer	84	9724.5	2	UniProt (P0AG63) Pfam (PF00366)	Escherichia coli K-12
17	Q, TB (AR, CR)	30S ribosomal protein S18	polymer	75	9005.5	2	UniProt (P0A7T7) Pfam (PF01084)	Escherichia coli K-12
18	R, UB (AS, CS)	30S ribosomal protein S19	polymer	92	10455.4	2	UniProt (P0A7U3) Pfam (PF00203)	Escherichia coli K-12
19	S, VB (AT, CT)	30S ribosomal protein S20	polymer	87	9708.5	2	UniProt (P0A7U7) Pfam (PF01649)	Escherichia coli K-12
20	T, WB (AU, CU)	30S ribosomal protein S21	polymer	71	8524.0	2	UniProt (P68679) Pfam (PF01165)	Escherichia coli K-12
21	U (AA)	16S rRNA	polymer	1533	496892.4	1		Escherichia coli
22	AC, V, X, YB (AV, AX, CV, CX)	P-site tRNA ASL fragment	polymer	17	5466.3	4
23	W, ZB (AW, CW)	messenger RNA	polymer	6	1792.0	2
24	BC, Y (BA, DA)	23S rRNA	polymer	2903	941306.2	2		Escherichia coli
25	Z (BB)	5S rRNA	polymer	118	38177.8	1		Escherichia coli
26	AA, DC (BC, DC)	50S ribosomal protein L2	polymer	273	29923.6	2	UniProt (P60422) Pfam (PF00181) Pfam (PF03947)	Escherichia coli K-12
27	BA, EC (BD, DD)	50S ribosomal protein L3	polymer	209	22277.5	2	UniProt (P60438) Pfam (PF00297)	Escherichia coli K-12
28	CA, FC (BE, DE)	50S ribosomal protein L4	polymer	201	22121.6	2	UniProt (P60723) Pfam (PF00573)	Escherichia coli K-12
29	DA, GC (BF, DF)	50S ribosomal protein L5	polymer	179	20333.6	2	UniProt (P62399) Pfam (PF00281) Pfam (PF00673)	Escherichia coli K-12
30	EA, HC (BG, DG)	50S ribosomal protein L6	polymer	177	18932.8	2	UniProt (P0AG55) Pfam (PF00347)	Escherichia coli K-12
31	FA, IC (BH, DH)	50S ribosomal protein L9	polymer	149	15789.0	2	UniProt (P0A7R1) Pfam (PF01281) Pfam (PF03948)	Escherichia coli K-12
32	GA, JC (BI, DI)	50S ribosomal protein L11	polymer	142	14894.4	2	UniProt (P0A7J7) Pfam (PF03946) Pfam (PF00298)	Escherichia coli K-12
33	HA, KC (BJ, DJ)	50S ribosomal protein L13	polymer	142	16050.6	2	UniProt (P0AA10) Pfam (PF00572)	Escherichia coli K-12
34	IA, LC (BK, DK)	50S ribosomal protein L14	polymer	123	13565.1	2	UniProt (P0ADY3) Pfam (PF00238)	Escherichia coli K-12
35	JA, MC (BL, DL)	50S ribosomal protein L15	polymer	144	15008.5	2	UniProt (P02413) Pfam (PF00828)	Escherichia coli K-12
36	KA, NC (BM, DM)	50S ribosomal protein L16	polymer	136	15312.3	2	UniProt (P0ADY7) Pfam (PF00252)	Escherichia coli K-12
37	LA, OC (BN, DN)	50S ribosomal protein L17	polymer	127	14393.7	2	UniProt (P0AG44) Pfam (PF01196)	Escherichia coli K-12
38	MA, PC (BO, DO)	50S ribosomal protein L18	polymer	117	12794.7	2	UniProt (P0C018) Pfam (PF00861)	Escherichia coli K-12
39	NA, QC (BP, DP)	50S ribosomal protein L19	polymer	115	13159.3	2	UniProt (P0A7K6) Pfam (PF01245)	Escherichia coli K-12
40	OA, RC (BQ, DQ)	50S ribosomal protein L20	polymer	118	13528.0	2	UniProt (P0A7L3) Pfam (PF00453)	Escherichia coli K-12
41	PA, SC (BR, DR)	50S ribosomal protein L21	polymer	103	11586.4	2	UniProt (P0AG48) Pfam (PF00829)	Escherichia coli K-12
42	QA, TC (BS, DS)	50S ribosomal protein L22	polymer	110	12253.4	2	UniProt (P61175) Pfam (PF00237)	Escherichia coli K-12
43	RA, UC (BT, DT)	50S ribosomal protein L23	polymer	100	11222.2	2	UniProt (P0ADZ0) Pfam (PF00276)	Escherichia coli K-12
44	SA, VC (BU, DU)	50S ribosomal protein L24	polymer	104	11339.3	2	UniProt (P60624) Pfam (PF00467) Pfam (PF17136)	Escherichia coli K-12
45	TA, WC (BV, DV)	50S ribosomal protein L25	polymer	94	10713.5	2	UniProt (P68919) Pfam (PF01386)	Escherichia coli K-12
46	UA, XC (BW, DW)	50S ribosomal protein L27	polymer	85	9146.5	2	UniProt (P0A7L8) Pfam (PF01016)	Escherichia coli K-12
47	VA, YC (BX, DX)	50S ribosomal protein L28	polymer	78	9027.6	2	UniProt (P0A7M2) Pfam (PF00830)	Escherichia coli K-12
48	WA, ZC (BY, DY)	50S ribosomal protein L29	polymer	63	7286.5	2	UniProt (P0A7M6) Pfam (PF00831)	Escherichia coli K-12
49	AD, XA (BZ, DZ)	50S ribosomal protein L30	polymer	59	6554.8	2	UniProt (P0AG51) Pfam (PF00327)	Escherichia coli K-12
50	BD, YA (B0, D0)	50S ribosomal protein L32	polymer	57	6463.4	2	UniProt (P0A7N4) Pfam (PF01783)	Escherichia coli K-12
51	CD, ZA (B1, D1)	50S ribosomal protein L33	polymer	55	6388.6	2	UniProt (P0A7N9) Pfam (PF00471)	Escherichia coli K-12
52	AB, DD (B2, D2)	50S ribosomal protein L34	polymer	46	5397.5	2	UniProt (P0A7P5) Pfam (PF00468)	Escherichia coli K-12
53	BB, ED (B3, D3)	50S ribosomal protein L35	polymer	65	7313.0	2	UniProt (P0A7Q1) Pfam (PF01632)	Escherichia coli K-12	Ribosomal protein A
54	CB, FD (B4, D4)	50S ribosomal protein L36	polymer	38	4377.4	2	UniProt (P0A7Q6) Pfam (PF00444)	Escherichia coli K-12	Ribosomal protein B
55	XB (CA)	16S rRNA	polymer	1530	495927.7	1		Escherichia coli
56	CC (DB)	5S rRNA	polymer	117	37848.6	1		Escherichia coli
57	AE, AF, AG, AH, AI... (AA, BA, CA, DA, DB...)	MAGNESIUM ION	non-polymer		24.3	363	Chemie (MG)
58	GR, IK (D4, B4)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
59	AS, BS, CS, DS, ES... (CL, CN, CT, CU, CA...)	water	water		18.0	1718	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	110
	Total formula weight	4310853.2
Non-Polymers*	Number of molecules	365
	Total formula weight	8953.5
All*	Total formula weight	4319806.8

*Water molecules are not included.