4V5K
Structure of cytotoxic domain of colicin E3 bound to the 70S ribosome
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AA, CA | 16S ribosomal RNA | polymer | 1522 | 494038.3 | 2 | GenBank (55979969) | Thermus thermophilus HB8 | |
2 | AB, CB | 30S RIBOSOMAL PROTEIN S2 | polymer | 256 | 29317.7 | 2 | UniProt (P80371) Pfam (PF00318) In PDB | Thermus thermophilus HB8 | |
3 | AC, CC | 30S RIBOSOMAL PROTEIN S3 | polymer | 239 | 26751.1 | 2 | UniProt (P80372) Pfam (PF07650) Pfam (PF00189) In PDB | Thermus thermophilus HB8 | |
4 | AD, CD | 30S RIBOSOMAL PROTEIN S4 | polymer | 209 | 24373.4 | 2 | UniProt (P80373) Pfam (PF00163) Pfam (PF01479) In PDB | Thermus thermophilus HB8 | |
5 | AE, CE | 30S RIBOSOMAL PROTEIN S5 | polymer | 162 | 17583.4 | 2 | UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719) In PDB | Thermus thermophilus HB8 | |
6 | AF, CF | 30S RIBOSOMAL PROTEIN S6 | polymer | 101 | 11988.8 | 2 | UniProt (Q5SLP8) Pfam (PF01250) In PDB | Thermus thermophilus HB8 | TS9 |
7 | AG, CG | 30S RIBOSOMAL PROTEIN S7 | polymer | 156 | 18051.0 | 2 | UniProt (P17291) Pfam (PF00177) In PDB | Thermus thermophilus HB8 | |
8 | AH, CH | 30S RIBOSOMAL PROTEIN S8 | polymer | 138 | 15868.6 | 2 | UniProt (Q5SHQ2) In PDB | Thermus thermophilus HB8 | |
9 | AI, CI | 30S RIBOSOMAL PROTEIN S9 | polymer | 128 | 14429.7 | 2 | UniProt (P80374) UniProt (P62669) Pfam (PF00380) In PDB | Thermus thermophilus HB8 | |
10 | AJ, CJ | 30S RIBOSOMAL PROTEIN S10 | polymer | 105 | 11955.0 | 2 | UniProt (Q5SHN7) Pfam (PF00338) In PDB | Thermus thermophilus HB8 | |
11 | AK, CK | 30S RIBOSOMAL PROTEIN S11 | polymer | 129 | 13737.9 | 2 | UniProt (P80376) Pfam (PF00411) In PDB | Thermus thermophilus HB8 | |
12 | AL, CL | 30S RIBOSOMAL PROTEIN S12 | polymer | 135 | 14920.8 | 2 | UniProt (Q5SHN3) Pfam (PF00164) In PDB | Thermus thermophilus HB8 | |
13 | AM, CM | 30S RIBOSOMAL PROTEIN S13 | polymer | 126 | 14338.9 | 2 | UniProt (P80377) Pfam (PF00416) In PDB | Thermus thermophilus HB8 | |
14 | AN, CN | 30S RIBOSOMAL PROTEIN S14 TYPE Z | polymer | 61 | 7158.7 | 2 | UniProt (Q5SHQ1) In PDB | Thermus thermophilus HB8 | 30S RIBOSOMAL PROTEIN S14 |
15 | AO, CO | 30S RIBOSOMAL PROTEIN S15 | polymer | 89 | 10578.4 | 2 | UniProt (Q5SJ76) Pfam (PF00312) In PDB | Thermus thermophilus HB8 | |
16 | AP, CP | 30S RIBOSOMAL PROTEIN S16 | polymer | 88 | 10410.0 | 2 | UniProt (Q5SJH3) Pfam (PF00886) In PDB | Thermus thermophilus HB8 | |
17 | AQ, CQ | 30S RIBOSOMAL PROTEIN S17 | polymer | 105 | 12325.7 | 2 | UniProt (Q5SHP7) In PDB | Thermus thermophilus HB8 | |
18 | AR, CR | 30S RIBOSOMAL PROTEIN S18 | polymer | 88 | 10258.3 | 2 | UniProt (Q5SLQ0) Pfam (PF01084) In PDB | Thermus thermophilus HB8 | |
19 | AS, CS | 30S RIBOSOMAL PROTEIN S19 | polymer | 93 | 10605.5 | 2 | UniProt (Q5SHP2) Pfam (PF00203) In PDB | Thermus thermophilus HB8 | |
20 | AT, CT | 30S RIBOSOMAL PROTEIN S20 | polymer | 106 | 11736.1 | 2 | UniProt (P80380) Pfam (PF01649) In PDB | Thermus thermophilus HB8 | |
21 | AU, CU | 30S RIBOSOMAL PROTEIN THX | polymer | 27 | 3350.0 | 2 | UniProt (Q5SIH3) Pfam (PF17070) In PDB | Thermus thermophilus HB8 | S31 |
22 | AV, AW, CV, CW | E-SITE TRNA PHE OR P-SITE TRNA PHE | polymer | 77 | 24802.8 | 4 | Escherichia coli K-12 | ||
23 | AX | MRNA | polymer | 25 | 8157.0 | 1 | synthetic construct | ||
24 | AY, CY | COLICIN-E3 | polymer | 97 | 10874.2 | 2 | UniProt (P00646) Pfam (PF09000) In PDB | Escherichia coli | COLICIN-E3 A CHAIN, RIBONUCLEASE |
25 | B0, D0 | 50S RIBOSOMAL PROTEIN L27 | polymer | 85 | 9529.1 | 2 | UniProt (P60493) Pfam (PF01016) In PDB | Thermus thermophilus HB8 | |
26 | B1, D1 | 50S RIBOSOMAL PROTEIN L28 | polymer | 98 | 11032.2 | 2 | UniProt (P60494) Pfam (PF00830) In PDB | Thermus thermophilus HB8 | |
27 | B2, D2 | 50S RIBOSOMAL PROTEIN L29 | polymer | 72 | 8670.3 | 2 | UniProt (Q5SHP6) Pfam (PF00831) In PDB | Thermus thermophilus HB8 | |
28 | B3, D3 | 50S RIBOSOMAL PROTEIN L30 | polymer | 60 | 6799.1 | 2 | UniProt (Q5SHQ6) Pfam (PF00327) In PDB | Thermus thermophilus HB8 | |
29 | B4, D4 | 50S RIBOSOMAL PROTEIN L31 | polymer | 71 | 8300.5 | 2 | UniProt (Q5SJE1) Pfam (PF01197) In PDB | Thermus thermophilus HB8 | |
30 | B5, D5 | 50S RIBOSOMAL PROTEIN L32 | polymer | 60 | 6722.1 | 2 | UniProt (P80339) Pfam (PF01783) In PDB | Thermus thermophilus HB8 | |
31 | B6, D6 | 50S RIBOSOMAL PROTEIN L33 | polymer | 54 | 6632.9 | 2 | UniProt (P35871) Pfam (PF00471) In PDB | Thermus thermophilus HB8 | |
32 | B7, D7 | 50S RIBOSOMAL PROTEIN L34 | polymer | 49 | 6132.4 | 2 | UniProt (P80340) Pfam (PF00468) In PDB | Thermus thermophilus HB8 | |
33 | B8, D8 | 50S RIBOSOMAL PROTEIN L35 | polymer | 65 | 7506.2 | 2 | UniProt (Q5SKU1) Pfam (PF01632) In PDB | Thermus thermophilus HB8 | |
34 | B9, D9 | 50S RIBOSOMAL PROTEIN L36 | polymer | 37 | 4435.4 | 2 | UniProt (Q5SHR2) Pfam (PF00444) In PDB | Thermus thermophilus HB8 | RIBOSOMAL PROTEIN B |
35 | BA, DA | 23S ribosomal RNA | polymer | 2848 | 926365.8 | 2 | Thermus thermophilus HB8 | ||
36 | BB, DB | 5S ribosomal RNA | polymer | 122 | 39494.5 | 2 | GenBank (55979969) | Thermus thermophilus HB8 | |
37 | BC, DC | 50S RIBOSOMAL PROTEIN L1 | polymer | 229 | 24872.7 | 2 | UniProt (Q5SLP7) Pfam (PF00687) In PDB | Thermus thermophilus HB8 | |
38 | BD, DD | 50S RIBOSOMAL PROTEIN L2 | polymer | 276 | 30532.6 | 2 | UniProt (P60405) Pfam (PF00181) Pfam (PF03947) In PDB | Thermus thermophilus HB8 | |
39 | BE, DE | 50S RIBOSOMAL PROTEIN L3 | polymer | 206 | 22450.2 | 2 | UniProt (Q5SHN8) Pfam (PF00297) In PDB | Thermus thermophilus HB8 | |
40 | BF, DF | 50S RIBOSOMAL PROTEIN L4 | polymer | 210 | 23271.9 | 2 | UniProt (Q5SHN9) Pfam (PF00573) In PDB | Thermus thermophilus HB8 | L1E |
41 | BG, DG | 50S RIBOSOMAL PROTEIN L5 | polymer | 182 | 21061.6 | 2 | UniProt (Q5SHQ0) Pfam (PF00281) Pfam (PF00673) In PDB | Thermus thermophilus HB8 | |
42 | BH, DH | 50S RIBOSOMAL PROTEIN L6 | polymer | 180 | 19568.9 | 2 | UniProt (Q5SHQ3) In PDB | Thermus thermophilus HB8 | |
43 | BI, DI | 50S RIBOSOMAL PROTEIN L9 | polymer | 148 | 16422.2 | 2 | UniProt (Q5SLQ1) Pfam (PF01281) Pfam (PF03948) In PDB | Thermus thermophilus HB8 | |
44 | BJ, DJ | 50S RIBOSOMAL PROTEIN L10 | polymer | 131 | 11166.8 | 2 | Thermus thermophilus HB8 | ||
45 | BN, DN | 50S RIBOSOMAL PROTEIN L13 | polymer | 140 | 15927.9 | 2 | UniProt (P60488) Pfam (PF00572) In PDB | Thermus thermophilus HB8 | |
46 | BO, DO | 50S RIBOSOMAL PROTEIN L14 | polymer | 122 | 13323.6 | 2 | UniProt (Q5SHP8) Pfam (PF00238) In PDB | Thermus thermophilus HB8 | |
47 | BP, DP | 50S RIBOSOMAL PROTEIN L15 | polymer | 150 | 16319.1 | 2 | UniProt (Q5SHQ7) Pfam (PF00828) In PDB | Thermus thermophilus HB8 | |
48 | BQ, DQ | 50S RIBOSOMAL PROTEIN L16 | polymer | 141 | 15993.9 | 2 | UniProt (P60489) Pfam (PF00252) In PDB | Thermus thermophilus HB8 | |
49 | BR, DR | 50S RIBOSOMAL PROTEIN L17 | polymer | 118 | 13750.1 | 2 | UniProt (Q9Z9H5) Pfam (PF01196) In PDB | Thermus thermophilus HB8 | |
50 | BS, DS | 50S RIBOSOMAL PROTEIN L18 | polymer | 112 | 12639.8 | 2 | UniProt (Q5SHQ4) Pfam (PF00861) In PDB | Thermus thermophilus HB8 | TL24 |
51 | BT, DT | 50S RIBOSOMAL PROTEIN L19 | polymer | 146 | 17188.8 | 2 | UniProt (P60490) Pfam (PF01245) In PDB | Thermus thermophilus HB8 | |
52 | BU, DU | 50S RIBOSOMAL PROTEIN L20 | polymer | 118 | 13779.3 | 2 | UniProt (P60491) Pfam (PF00453) In PDB | Thermus thermophilus HB8 | |
53 | BV, DV | 50S RIBOSOMAL PROTEIN L21 | polymer | 101 | 11069.2 | 2 | UniProt (P60492) Pfam (PF00829) In PDB | Thermus thermophilus HB8 | |
54 | BW, DW | 50S RIBOSOMAL PROTEIN L22 | polymer | 113 | 12808.1 | 2 | UniProt (Q5SHP3) Pfam (PF00237) In PDB | Thermus thermophilus HB8 | |
55 | BX, DX | 50S RIBOSOMAL PROTEIN L23 | polymer | 96 | 10759.8 | 2 | UniProt (Q5SHP0) Pfam (PF00276) In PDB | Thermus thermophilus HB8 | |
56 | BY, DY | 50S RIBOSOMAL PROTEIN L24 | polymer | 110 | 12085.6 | 2 | UniProt (Q5SHP9) Pfam (PF00467) Pfam (PF17136) In PDB | Thermus thermophilus HB8 | |
57 | BZ, DZ | 50S RIBOSOMAL PROTEIN L25 | polymer | 206 | 23238.6 | 2 | UniProt (Q5SHZ1) Pfam (PF01386) Pfam (PF14693) In PDB | Thermus thermophilus HB8 | TL5 |
58 | CX | MRNA | polymer | 25 | 8196.0 | 1 | synthetic construct | ||
59 | BA, CA, DA, AA, CV... | MAGNESIUM ION | non-polymer | 24.3 | 2334 | Chemie (MG) | |||
60 | AD, AN, CD | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
61 | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
AI, CI: 1 - 128 (UniProt: P62669)
AY, CY: 0 - 96 (UniProt: P00646)
B1, D1: 1 - 98 (UniProt: P60494)
AY, CY: 0 - 96 (UniProt: P00646)
PDB | External Database | Details |
---|---|---|
Ala 58 | His 45 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Arg 81 | Lys 81 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 116 |
Total formula weight | 4504569.1 | |
Non-Polymers* | Number of molecules | 2338 |
Total formula weight | 56989.5 | |
All* | Total formula weight | 4561558.6 |