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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

4V5G

The crystal structure of the 70S ribosome bound to EF-Tu and tRNA

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, HB
(AA, CA)		16S RIBOSOMAL RNApolymer1522493958.32GenBank (55979969)THERMUS THERMOPHILUS16S RRNA
2B, IB
(AB, CB)		30S RIBOSOMAL PROTEIN S2polymer25629317.72UniProt (P80371)
Pfam (PF00318)		THERMUS THERMOPHILUS
3C, JB
(AC, CC)		30S RIBOSOMAL PROTEIN S3polymer23926751.12UniProt (P80372)
Pfam (PF07650)
Pfam (PF00189)		THERMUS THERMOPHILUS
4D, KB
(AD, CD)		30S RIBOSOMAL PROTEIN S4polymer20924373.42UniProt (P80373)
Pfam (PF00163)
Pfam (PF01479)		THERMUS THERMOPHILUS
5E, LB
(AE, CE)		30S RIBOSOMAL PROTEIN S5polymer16217583.42UniProt (Q5SHQ5)
Pfam (PF00333)
Pfam (PF03719)		THERMUS THERMOPHILUS
6F, MB
(AF, CF)		30S RIBOSOMAL PROTEIN S6polymer10111988.82UniProt (Q5SLP8)
Pfam (PF01250)		THERMUS THERMOPHILUSTS9
7G, NB
(AG, CG)		30S RIBOSOMAL PROTEIN S7polymer15618051.02UniProt (P17291)
Pfam (PF00177)		THERMUS THERMOPHILUS
8H, OB
(AH, CH)		30S RIBOSOMAL PROTEIN S8polymer13815868.62UniProt (Q5SHQ2)
Pfam (PF00410)
UniProt (by SIFTS) (P0DOY9)		THERMUS THERMOPHILUS
9I, PB
(AI, CI)		30S RIBOSOMAL PROTEIN S9polymer12814410.62UniProt (P80374)
Pfam (PF00380)		THERMUS THERMOPHILUS
10J, QB
(AJ, CJ)		30S RIBOSOMAL PROTEIN S10polymer10511955.02UniProt (Q5SHN7)
Pfam (PF00338)		THERMUS THERMOPHILUS
11K, RB
(AK, CK)		30S RIBOSOMAL PROTEIN S11polymer12913737.92UniProt (P80376)
Pfam (PF00411)		THERMUS THERMOPHILUS
12L, SB
(AL, CL)		30S RIBOSOMAL PROTEIN S12polymer13514920.82UniProt (Q5SHN3)
Pfam (PF00164)		THERMUS THERMOPHILUS
13M, TB
(AM, CM)		30S RIBOSOMAL PROTEIN S13polymer12614338.92UniProt (P80377)
Pfam (PF00416)		THERMUS THERMOPHILUS
14N, UB
(AN, CN)		30S RIBOSOMAL PROTEIN S14 TYPE Zpolymer617158.72UniProt (Q5SHQ1)
Pfam (PF00253)
UniProt (by SIFTS) (P0DOY6)		THERMUS THERMOPHILUS
15O, VB
(AO, CO)		30S RIBOSOMAL PROTEIN S15polymer8910578.42UniProt (Q5SJ76)
Pfam (PF00312)		THERMUS THERMOPHILUS
16P, WB
(AP, CP)		30S RIBOSOMAL PROTEIN S16polymer8810410.02UniProt (Q5SJH3)
Pfam (PF00886)		THERMUS THERMOPHILUS
17Q, XB
(AQ, CQ)		30S RIBOSOMAL PROTEIN S17polymer10512325.72UniProt (Q5SHP7)
Pfam (PF00366)
UniProt (by SIFTS) (P0DOY7)		THERMUS THERMOPHILUS
18R, YB
(AR, CR)		30S RIBOSOMAL PROTEIN S18polymer8810258.32UniProt (Q5SLQ0)
Pfam (PF01084)		THERMUS THERMOPHILUS
19S, ZB
(AS, CS)		30S RIBOSOMAL PROTEIN S19polymer9310605.52UniProt (Q5SHP2)
Pfam (PF00203)		THERMUS THERMOPHILUS
20AC, T
(AT, CT)		30S RIBOSOMAL PROTEIN S20polymer10611736.12UniProt (P80380)
Pfam (PF01649)		THERMUS THERMOPHILUS
21BC, U
(AU, CU)		30S RIBOSOMAL PROTEIN THXpolymer273350.02UniProt (Q5SIH3)
Pfam (PF17070)		THERMUS THERMOPHILUSS31
22CC, DC, V, W
(AV, AW, CV, CW)		E-SITE TRNA PHE OR P-SITE TRNA PHEpolymer7624485.54ESCHERICHIA COLI
23EC, X
(AX, CX)		MRNApolymer278767.32synthetic construct
24FC, Y
(AY, CY)		A-SITE TRNA THRpolymer7724874.02THERMUS THERMOPHILUS
25GC, Z
(AZ, CZ)		ELONGATION FACTOR TU-Apolymer40644841.02UniProt (Q5SHN6)
Pfam (PF00009)
Pfam (PF03144)
Pfam (PF03143)		THERMUS THERMOPHILUSELONGATION FACTOR TU, EF-TU-A
26AA, HC
(B0, D0)		50S RIBOSOMAL PROTEIN L27polymer859529.12UniProt (P60493)
Pfam (PF01016)		THERMUS THERMOPHILUS
27BA, IC
(B1, D1)		50S RIBOSOMAL PROTEIN L28polymer9811004.22UniProt (P60494)
Pfam (PF00830)		THERMUS THERMOPHILUS
28CA, JC
(B2, D2)		50S RIBOSOMAL PROTEIN L29polymer728670.32UniProt (Q5SHP6)
Pfam (PF00831)		THERMUS THERMOPHILUSTL5
29DA, KC
(B3, D3)		50S RIBOSOMAL PROTEIN L30polymer606799.12UniProt (Q5SHQ6)
Pfam (PF00327)		THERMUS THERMOPHILUS
30EA, LC
(B4, D4)		50S RIBOSOMAL PROTEIN L31polymer718300.52UniProt (Q5SJE1)
Pfam (PF01197)		THERMUS THERMOPHILUS
31FA, MC
(B5, D5)		50S RIBOSOMAL PROTEIN L32polymer606722.12UniProt (P80339)
Pfam (PF01783)		THERMUS THERMOPHILUS
32GA, NC
(B6, D6)		50S RIBOSOMAL PROTEIN L33polymer546632.92UniProt (P35871)
Pfam (PF00471)		THERMUS THERMOPHILUS
33HA, OC
(B7, D7)		50S RIBOSOMAL PROTEIN L34polymer496132.42UniProt (P80340)
Pfam (PF00468)		THERMUS THERMOPHILUS
34IA, PC
(B8, D8)		50S RIBOSOMAL PROTEIN L35polymer657506.22UniProt (Q5SKU1)
Pfam (PF01632)		THERMUS THERMOPHILUS
35JA, QC
(B9, D9)		50S RIBOSOMAL PROTEIN L36polymer374435.42UniProt (Q5SHR2)
Pfam (PF00444)		THERMUS THERMOPHILUSRIBOSOMAL PROTEIN B
36KA, RC
(BA, DA)		23S RIBOSOMAL RNApolymer2915947935.42GenBank (55979969)THERMUS THERMOPHILUS
37LA, SC
(BB, DB)		5S RIBOSOMAL RNApolymer12239540.62GenBank (55979969)
GenBank (48257)		THERMUS THERMOPHILUS
38MA, TC
(BC, DC)		50S RIBOSOMAL PROTEIN L1polymer22924872.72UniProt (Q5SLP7)
Pfam (PF00687)		THERMUS THERMOPHILUS
39NA, UC
(BD, DD)		50S RIBOSOMAL PROTEIN L2polymer27630532.62UniProt (P60405)
Pfam (PF00181)
Pfam (PF03947)		THERMUS THERMOPHILUS
40OA, VC
(BE, DE)		50S RIBOSOMAL PROTEIN L3polymer20622450.22UniProt (Q5SHN8)
Pfam (PF00297)		THERMUS THERMOPHILUS
41PA, WC
(BF, DF)		50S RIBOSOMAL PROTEIN L4polymer21023271.92UniProt (Q5SHN9)
Pfam (PF00573)		THERMUS THERMOPHILUSL1E
42QA, XC
(BG, DG)		50S RIBOSOMAL PROTEIN L5polymer18221061.62UniProt (Q5SHQ0)
Pfam (PF00281)
Pfam (PF00673)		THERMUS THERMOPHILUS
43RA, YC
(BH, DH)		50S RIBOSOMAL PROTEIN L6polymer18019568.92UniProt (Q5SHQ3)
Pfam (PF00347)
UniProt (by SIFTS) (P0DOY8)		THERMUS THERMOPHILUS
44SA, ZC
(BJ, DJ)		50S RIBOSOMAL PROTEIN L10polymer17314741.12THERMUS THERMOPHILUS
45AD, TA
(BK, DK)		50S RIBOSOMAL PROTEIN L11polymer14712528.42THERMUS THERMOPHILUS
46BD, UA
(BN, DN)		50S RIBOSOMAL PROTEIN L13polymer14015927.92UniProt (P60488)
Pfam (PF00572)		THERMUS THERMOPHILUS
47CD, VA
(BO, DO)		50S RIBOSOMAL PROTEIN L14polymer12213323.62UniProt (Q5SHP8)
Pfam (PF00238)		THERMUS THERMOPHILUS
48DD, WA
(BP, DP)		50S RIBOSOMAL PROTEIN L15polymer15016319.12UniProt (Q5SHQ7)
Pfam (PF00828)		THERMUS THERMOPHILUS
49ED, XA
(BQ, DQ)		50S RIBOSOMAL PROTEIN L16polymer14115993.92UniProt (P60489)
Pfam (PF00252)		THERMUS THERMOPHILUS
50FD, YA
(BR, DR)		50S RIBOSOMAL PROTEIN L17polymer11813750.12UniProt (Q9Z9H5)
Pfam (PF01196)		THERMUS THERMOPHILUS
51GD, ZA
(BS, DS)		50S RIBOSOMAL PROTEIN L18polymer11212639.82UniProt (Q5SHQ4)
Pfam (PF00861)		THERMUS THERMOPHILUSTL24
52AB, HD
(BT, DT)		50S RIBOSOMAL PROTEIN L19polymer14617188.82UniProt (P60490)
Pfam (PF01245)		THERMUS THERMOPHILUS
53BB, ID
(BU, DU)		50S RIBOSOMAL PROTEIN L20polymer11813779.32UniProt (P60491)
Pfam (PF00453)		THERMUS THERMOPHILUS
54CB, JD
(BV, DV)		50S RIBOSOMAL PROTEIN L21polymer10111069.22UniProt (P60492)
Pfam (PF00829)		THERMUS THERMOPHILUS
55DB, KD
(BW, DW)		50S RIBOSOMAL PROTEIN L22polymer11312808.12UniProt (Q5SHP3)
Pfam (PF00237)		THERMUS THERMOPHILUS
56EB, LD
(BX, DX)		50S RIBOSOMAL PROTEIN L23polymer9610759.82UniProt (Q5SHP0)
Pfam (PF00276)		THERMUS THERMOPHILUS
57FB, MD
(BY, DY)		50S RIBOSOMAL PROTEIN L24polymer11012085.62UniProt (Q5SHP9)
Pfam (PF00467)
Pfam (PF17136)		THERMUS THERMOPHILUS
58GB, ND
(BZ, DZ)		50S RIBOSOMAL PROTEIN L25polymer20623238.62UniProt (Q5SHZ1)
Pfam (PF01386)
Pfam (PF14693)		THERMUS THERMOPHILUSTL5
59OD, WD
(AA, CA)		PAROMOMYCINnon-polymer615.62Chemie (PAR)
PubChem (16757804)
PubChem (16760604)
PubChem (17757254)
PubChem (20849281)
PubChem (71191297)
PubChem (165580)
PubChem (23789070)
PubChem (24096964)
PubChem (24867526)
PubChem (24867858)
PubChem (25104843)
PubChem (71188564)
PubChem (44120093)
PubChem (44251565)
PubChem (44186758)
PubChem (44663324)
PubChem (45358711)
PubChem (53486370)
PubChem (50989619)
PubChem (58160567)
PubChem (59361026)
PubChem (59800245)
PubChem (70793652)
PubChem (70793824)
PubChem (70795918)
PubChem (71068776)
PubChem (71072581)
PubChem (71072592)
PubChem (66932615)
PubChem (68032118)
PubChem (4689)
PubChem (14951)
PubChem (24176)
PubChem (6602492)
PubChem (6713982)
PubChem (70878598)
PubChem (71751432)
PubChem (91151908)
PubChem (73707499)
PubChem (9961808)
PubChem (3040200)
PubChem (94469269)
PubChem (94469270)
PubChem (94469271)
PubChem (91867972)
PubChem (98048758)
PubChem (98048760)
PubChem (91972181)
PubChem (94469268)
PubChem (98048759)
PubChem (98048761)
PubChem (5702262)
PubChem (121292209)
PubChem (6603975)
PubChem (101739930)
PubChem (6604293)
PubChem (122537356)
PubChem (6710686)
PubChem (124226135)
PubChem (124464537)
PubChem (9809147)
PubChem (125040357)
PubChem (125040359)
PubChem (125121197)
PubChem (129009945)
PubChem (131841783)
PubChem (132275078)
PubChem (118213779)
PubChem (118705495)
PubChem (122691713)
PubChem (124226132)
PubChem (124226133)
PubChem (124226134)
PubChem (124464538)
PubChem (12313981)
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PubChem (124761787)
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PubChem (125040358)
PubChem (125040360)
PubChem (125121198)
PubChem (129014632)
PubChem (129014634)
PubChem (129014635)
PubChem (129313238)
PubChem (152952600)
PubChem (134771120)
PubChem (162873319)
PubChem (137404838)
PubChem (161153506)
PubChem (163199098)
PubChem (164850471)
PubChem (172091638)
PubChem (173719997)
60CE, DE, PD, QD, UD...
(D4, D9, AD, AN, B4...)		ZINC IONnon-polymer65.48Chemie (ZN)
61RD, ZD
(AY, CY)		MAGNESIUM IONnon-polymer24.32Chemie (MG)
PubChem (888)
62AE, SD
(CZ, AZ)		GUANOSINE-5'-DIPHOSPHATEnon-polymer443.22Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
63BE, TD
(CZ, AZ)		KIRROMYCINnon-polymer796.92Chemie (KIR)
Sequence modifications
AL, CL: 1 - 4 (PDB: 4V5G)
AL, CL: 5 - 135 (UniProt: Q5SHN3)
BB, DB: -1 - 120 (GenBank: 55979969)
BB, DB: -1 - 120 (GenBank: 48257)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains118
Total formula weight4664502.0
Non-Polymers*Number of molecules16
Total formula weight4283.4
All*Total formula weight4668785.5
*Water molecules are not included.

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PDB entries from 2026-04-01

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