4V51
Structure of the Thermus thermophilus 70S ribosome complexed with mRNA, tRNA and paromomycin
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, EB (AA, CA) | 16S ribosomal RNA | polymer | 1522 | 493958.3 | 2 | THERMUS THERMOPHILUS | ||
| 2 | B, FB (AB, CB) | 30S RIBOSOMAL PROTEIN S2 | polymer | 256 | 29317.7 | 2 | UniProt (P80371) Pfam (PF00318) | THERMUS THERMOPHILUS | |
| 3 | C, GB (AC, CC) | 30S RIBOSOMAL PROTEIN S3 | polymer | 239 | 26751.1 | 2 | UniProt (P80372) Pfam (PF07650) Pfam (PF00189) | THERMUS THERMOPHILUS | |
| 4 | D, HB (AD, CD) | 30S RIBOSOMAL PROTEIN S4 | polymer | 209 | 24373.4 | 2 | UniProt (P80373) Pfam (PF00163) Pfam (PF01479) | THERMUS THERMOPHILUS | |
| 5 | E, IB (AE, CE) | 30S RIBOSOMAL PROTEIN S5 | polymer | 162 | 17583.4 | 2 | UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719) | THERMUS THERMOPHILUS | |
| 6 | F, JB (AF, CF) | 30S RIBOSOMAL PROTEIN S6 | polymer | 101 | 11988.8 | 2 | UniProt (Q5SLP8) Pfam (PF01250) | THERMUS THERMOPHILUS | TS9 |
| 7 | G, KB (AG, CG) | 30S RIBOSOMAL PROTEIN S7 | polymer | 156 | 18051.0 | 2 | UniProt (P17291) Pfam (PF00177) | THERMUS THERMOPHILUS | |
| 8 | H, LB (AH, CH) | 30S RIBOSOMAL PROTEIN S8 | polymer | 138 | 15868.6 | 2 | UniProt (Q5SHQ2) | THERMUS THERMOPHILUS | |
| 9 | I, MB (AI, CI) | 30S RIBOSOMAL PROTEIN S9 | polymer | 128 | 14429.7 | 2 | UniProt (P62669) Pfam (PF00380) | THERMUS THERMOPHILUS | |
| 10 | J, NB (AJ, CJ) | 30S RIBOSOMAL PROTEIN S10 | polymer | 105 | 11955.0 | 2 | UniProt (Q5SHN7) Pfam (PF00338) | THERMUS THERMOPHILUS | |
| 11 | K, OB (AK, CK) | 30S RIBOSOMAL PROTEIN S11 | polymer | 129 | 13737.9 | 2 | UniProt (P80376) Pfam (PF00411) | THERMUS THERMOPHILUS | |
| 12 | L, PB (AL, CL) | 30S RIBOSOMAL PROTEIN S12 | polymer | 135 | 14920.8 | 2 | UniProt (Q5SHN3) Pfam (PF00164) | THERMUS THERMOPHILUS | |
| 13 | M, QB (AM, CM) | 30S RIBOSOMAL PROTEIN S13 | polymer | 126 | 14338.9 | 2 | UniProt (P80377) Pfam (PF00416) | THERMUS THERMOPHILUS | |
| 14 | N, RB (AN, CN) | 30S RIBOSOMAL PROTEIN S14 | polymer | 61 | 7158.7 | 2 | UniProt (Q5SHQ1) | THERMUS THERMOPHILUS | |
| 15 | O, SB (AO, CO) | 30S RIBOSOMAL PROTEIN S15 | polymer | 89 | 10578.4 | 2 | UniProt (Q5SJ76) Pfam (PF00312) | THERMUS THERMOPHILUS | |
| 16 | P, TB (AP, CP) | 30S RIBOSOMAL PROTEIN S16 | polymer | 88 | 10410.0 | 2 | UniProt (Q5SJH3) Pfam (PF00886) | THERMUS THERMOPHILUS | |
| 17 | Q, UB (AQ, CQ) | 30S RIBOSOMAL PROTEIN S17 | polymer | 105 | 12325.7 | 2 | UniProt (Q5SHP7) | THERMUS THERMOPHILUS | |
| 18 | R, VB (AR, CR) | 30S RIBOSOMAL PROTEIN S18 | polymer | 88 | 10258.3 | 2 | UniProt (Q5SLQ0) Pfam (PF01084) | THERMUS THERMOPHILUS | |
| 19 | S, WB (AS, CS) | 30S RIBOSOMAL PROTEIN S19 | polymer | 93 | 10605.5 | 2 | UniProt (Q5SHP2) Pfam (PF00203) | THERMUS THERMOPHILUS | |
| 20 | T, XB (AT, CT) | 30S RIBOSOMAL PROTEIN S20 | polymer | 106 | 11736.1 | 2 | UniProt (P80380) Pfam (PF01649) | THERMUS THERMOPHILUS | |
| 21 | U, YB (AU, CU) | 30S RIBOSOMAL PROTEIN THX | polymer | 27 | 3350.0 | 2 | UniProt (Q5SIH3) Pfam (PF17070) | THERMUS THERMOPHILUS | |
| 22 | V, ZB (AV, CV) | P-SITE TRNA FMET (UNMODIFIED BASES EXCEPT FOR THYMINE 54) | polymer | 77 | 24816.8 | 2 | Escherichia coli K-12 | ||
| 23 | AC, CC, W, Y (AW, AY, CW, CY) | E-SITE TRNA PHE OR A-SITE TRNA PHE (UNMODIFIED BASES) | polymer | 76 | 24485.5 | 4 | Escherichia coli K-12 | ||
| 24 | BC, X (AX, CX) | MRNA | polymer | 24 | 7827.8 | 2 | synthetic construct | ||
| 25 | DC, Z (B0, D0) | 50S RIBOSOMAL PROTEIN L27 | polymer | 85 | 9529.1 | 2 | UniProt (P60493) Pfam (PF01016) | THERMUS THERMOPHILUS | |
| 26 | AA, EC (B1, D1) | 50S RIBOSOMAL PROTEIN L28 | polymer | 98 | 11004.2 | 2 | UniProt (P60494) Pfam (PF00830) | THERMUS THERMOPHILUS | |
| 27 | BA, FC (B2, D2) | 50S RIBOSOMAL PROTEIN L29 | polymer | 72 | 8670.3 | 2 | UniProt (Q5SHP6) Pfam (PF00831) | THERMUS THERMOPHILUS | |
| 28 | CA, GC (B3, D3) | 50S RIBOSOMAL PROTEIN L30 | polymer | 60 | 6799.1 | 2 | UniProt (Q5SHQ6) Pfam (PF00327) | THERMUS THERMOPHILUS | |
| 29 | DA, HC (B4, D4) | 50S RIBOSOMAL PROTEIN L31 | polymer | 71 | 8300.5 | 2 | UniProt (Q5SJE1) Pfam (PF01197) | THERMUS THERMOPHILUS | |
| 30 | EA, IC (B5, D5) | 50S RIBOSOMAL PROTEIN L32 | polymer | 60 | 6722.1 | 2 | UniProt (P80339) Pfam (PF01783) | THERMUS THERMOPHILUS | |
| 31 | FA, JC (B6, D6) | 50S RIBOSOMAL PROTEIN L33 | polymer | 54 | 6632.9 | 2 | UniProt (P35871) Pfam (PF00471) | THERMUS THERMOPHILUS | |
| 32 | GA, KC (B7, D7) | 50S RIBOSOMAL PROTEIN L34 | polymer | 49 | 6132.4 | 2 | UniProt (P80340) Pfam (PF00468) | THERMUS THERMOPHILUS | |
| 33 | HA, LC (B8, D8) | 50S RIBOSOMAL PROTEIN L35 | polymer | 65 | 7506.2 | 2 | UniProt (P80341) Pfam (PF01632) UniProt (by SIFTS) (Q5SKU1) | THERMUS THERMOPHILUS | |
| 34 | IA, MC (BA, DA) | 23S RIBOSOMAL RNA | polymer | 2787 | 906447.8 | 2 | THERMUS THERMOPHILUS | ||
| 35 | JA, NC (BB, DB) | 5S RIBOSOMAL RNA | polymer | 122 | 39494.5 | 2 | THERMUS THERMOPHILUS | ||
| 36 | KA, OC (BC, DC) | 50S RIBOSOMAL PROTEIN L1 | polymer | 229 | 24872.7 | 2 | UniProt (Q5SLP7) Pfam (PF00687) | THERMUS THERMOPHILUS | |
| 37 | LA, PC (BD, DD) | 50S RIBOSOMAL PROTEIN L2 | polymer | 276 | 30532.6 | 2 | UniProt (P60405) Pfam (PF00181) Pfam (PF03947) | THERMUS THERMOPHILUS | |
| 38 | MA, QC (BE, DE) | 50S RIBOSOMAL PROTEIN L3 | polymer | 206 | 22450.2 | 2 | UniProt (Q5SHN8) Pfam (PF00297) | THERMUS THERMOPHILUS | |
| 39 | NA, RC (BF, DF) | 50S RIBOSOMAL PROTEIN L4 | polymer | 210 | 23271.9 | 2 | UniProt (Q5SHN9) Pfam (PF00573) | THERMUS THERMOPHILUS | |
| 40 | OA, SC (BG, DG) | 50S RIBOSOMAL PROTEIN L5 | polymer | 182 | 21061.6 | 2 | UniProt (Q5SHQ0) Pfam (PF00281) Pfam (PF00673) | THERMUS THERMOPHILUS | |
| 41 | PA, TC (BH, DH) | 50S RIBOSOMAL PROTEIN L6 | polymer | 180 | 19568.9 | 2 | UniProt (Q5SHQ3) | THERMUS THERMOPHILUS | |
| 42 | QA, UC (BI, DI) | 50S RIBOSOMAL PROTEIN L9 | polymer | 148 | 16422.2 | 2 | UniProt (Q5SLQ1) Pfam (PF01281) Pfam (PF03948) | THERMUS THERMOPHILUS | |
| 43 | RA, VC (BN, DN) | 50S RIBOSOMAL PROTEIN L13 | polymer | 140 | 15927.9 | 2 | UniProt (P60488) Pfam (PF00572) | THERMUS THERMOPHILUS | |
| 44 | SA, WC (BO, DO) | 50S RIBOSOMAL PROTEIN L14 | polymer | 122 | 13323.6 | 2 | UniProt (Q5SHP8) Pfam (PF00238) | THERMUS THERMOPHILUS | |
| 45 | TA, XC (BP, DP) | 50S RIBOSOMAL PROTEIN L15 | polymer | 150 | 16319.1 | 2 | UniProt (Q5SHQ7) Pfam (PF00828) | THERMUS THERMOPHILUS | |
| 46 | UA, YC (BQ, DQ) | 50S RIBOSOMAL PROTEIN L16 | polymer | 141 | 15993.9 | 2 | UniProt (P60489) Pfam (PF00252) | THERMUS THERMOPHILUS | |
| 47 | VA, ZC (BR, DR) | 50S RIBOSOMAL PROTEIN L17 | polymer | 118 | 13750.1 | 2 | UniProt (Q9Z9H5) Pfam (PF01196) | THERMUS THERMOPHILUS | |
| 48 | AD, WA (BS, DS) | 50S RIBOSOMAL PROTEIN L18 | polymer | 112 | 12639.8 | 2 | UniProt (Q5SHQ4) Pfam (PF00861) | THERMUS THERMOPHILUS | |
| 49 | BD, XA (BT, DT) | 50S RIBOSOMAL PROTEIN L19 | polymer | 146 | 17188.8 | 2 | UniProt (P60490) Pfam (PF01245) | THERMUS THERMOPHILUS | |
| 50 | CD, YA (BU, DU) | 50S RIBOSOMAL PROTEIN L20 | polymer | 118 | 13779.3 | 2 | UniProt (P60491) Pfam (PF00453) | THERMUS THERMOPHILUS | |
| 51 | DD, ZA (BV, DV) | 50S RIBOSOMAL PROTEIN L21 | polymer | 101 | 11069.2 | 2 | UniProt (P60492) Pfam (PF00829) | THERMUS THERMOPHILUS | |
| 52 | AB, ED (BW, DW) | 50S RIBOSOMAL PROTEIN L22 | polymer | 113 | 12808.1 | 2 | UniProt (Q5SHP3) Pfam (PF00237) | THERMUS THERMOPHILUS | |
| 53 | BB, FD (BX, DX) | 50S RIBOSOMAL PROTEIN L23 | polymer | 96 | 10759.8 | 2 | UniProt (Q5SHP0) Pfam (PF00276) | THERMUS THERMOPHILUS | |
| 54 | CB, GD (BY, DY) | 50S RIBOSOMAL PROTEIN L24 | polymer | 110 | 12085.6 | 2 | UniProt (Q5SHP9) Pfam (PF00467) Pfam (PF17136) | THERMUS THERMOPHILUS | |
| 55 | DB, HD (BZ, DZ) | 50S RIBOSOMAL PROTEIN L25 | polymer | 206 | 23238.6 | 2 | UniProt (Q5SHZ1) Pfam (PF01386) Pfam (PF14693) | THERMUS THERMOPHILUS | |
| 56 | AAA, AAB, ABA, ABB, ACA... (BA, DA, AA, DB, BB...) | MAGNESIUM ION | non-polymer | 24.3 | 1379 | Chemie (MG) | |||
| 57 | FNA, PL (CA, AA) | PAROMOMYCIN | non-polymer | 615.6 | 2 | Chemie (PAR) | |||
| 58 | GNA, KNA, QL, SL (CD, CN, AD, AN) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
AB, CB: 1 - 1 (PDB: 4V51)
AB, CB: 2 - 256 (UniProt: P80371)
AC, CC: 1 - 1 (PDB: 4V51)
AC, CC: 2 - 239 (UniProt: P80372)
AD, CD: 1 - 1 (PDB: 4V51)
AD, CD: 2 - 209 (UniProt: P80373)
AE, CE: 1 - 1 (PDB: 4V51)
AE, CE: 2 - 162 (UniProt: Q5SHQ5)
AG, CG: 1 - 1 (PDB: 4V51)
AG, CG: 2 - 156 (UniProt: P17291)
AJ, CJ: 1 - 1 (PDB: 4V51)
AJ, CJ: 2 - 105 (UniProt: Q5SHN7)
AK, CK: 1 - 1 (PDB: 4V51)
AK, CK: 2 - 129 (UniProt: P80376)
AL, CL: 1 - 4 (PDB: 4V51)
AL, CL: 5 - 135 (UniProt: Q5SHN3)
AM, CM: 1 - 1 (PDB: 4V51)
AM, CM: 2 - 126 (UniProt: P80377)
AN, CN: 1 - 1 (PDB: 4V51)
AN, CN: 2 - 61 (UniProt: Q5SHQ1)
AO, CO: 1 - 1 (PDB: 4V51)
AO, CO: 2 - 89 (UniProt: Q5SJ76)
AQ, CQ: 1 - 1 (PDB: 4V51)
AQ, CQ: 2 - 105 (UniProt: Q5SHP7)
AR, CR: 1 - 1 (PDB: 4V51)
AR, CR: 2 - 88 (UniProt: Q5SLQ0)
AS, CS: 1 - 1 (PDB: 4V51)
AS, CS: 2 - 93 (UniProt: Q5SHP2)
AT, CT: 1 - 1 (PDB: 4V51)
AT, CT: 2 - 106 (UniProt: P80380)
AU, CU: 1 - 1 (PDB: 4V51)
AU, CU: 2 - 27 (UniProt: Q5SIH3)
B0, D0: 1 - 1 (PDB: 4V51)
B0, D0: 2 - 85 (UniProt: P60493)
B1, D1: 1 - 1 (PDB: 4V51)
B1, D1: 2 - 98 (UniProt: P60494)
B3, D3: 1 - 1 (PDB: 4V51)
B3, D3: 2 - 60 (UniProt: Q5SHQ6)
B5, D5: 1 - 1 (PDB: 4V51)
B5, D5: 2 - 60 (UniProt: P80339)
B6, D6: 1 - 1 (PDB: 4V51)
B6, D6: 2 - 54 (UniProt: P35871)
B8, D8: 1 - 1 (PDB: 4V51)
B8, D8: 2 - 65 (UniProt: P80341)
BC, DC: 0 - 0 (PDB: 4V51)
BC, DC: 1 - 228 (UniProt: Q5SLP7)
BD, DD: 1 - 1 (PDB: 4V51)
BD, DD: 2 - 276 (UniProt: P60405)
BG, DG: 1 - 1 (PDB: 4V51)
BG, DG: 2 - 182 (UniProt: Q5SHQ0)
BH, DH: 1 - 1 (PDB: 4V51)
BH, DH: 2 - 180 (UniProt: Q5SHQ3)
BS, DS: 1 - 1 (PDB: 4V51)
BS, DS: 2 - 112 (UniProt: Q5SHQ4)
BU, DU: 1 - 1 (PDB: 4V51)
BU, DU: 2 - 118 (UniProt: P60491)
AB, CB: 2 - 256 (UniProt: P80371)
AC, CC: 1 - 1 (PDB: 4V51)
AC, CC: 2 - 239 (UniProt: P80372)
AD, CD: 1 - 1 (PDB: 4V51)
AD, CD: 2 - 209 (UniProt: P80373)
AE, CE: 1 - 1 (PDB: 4V51)
AE, CE: 2 - 162 (UniProt: Q5SHQ5)
AG, CG: 1 - 1 (PDB: 4V51)
AG, CG: 2 - 156 (UniProt: P17291)
AJ, CJ: 1 - 1 (PDB: 4V51)
AJ, CJ: 2 - 105 (UniProt: Q5SHN7)
AK, CK: 1 - 1 (PDB: 4V51)
AK, CK: 2 - 129 (UniProt: P80376)
AL, CL: 1 - 4 (PDB: 4V51)
AL, CL: 5 - 135 (UniProt: Q5SHN3)
AM, CM: 1 - 1 (PDB: 4V51)
AM, CM: 2 - 126 (UniProt: P80377)
AN, CN: 1 - 1 (PDB: 4V51)
AN, CN: 2 - 61 (UniProt: Q5SHQ1)
AO, CO: 1 - 1 (PDB: 4V51)
AO, CO: 2 - 89 (UniProt: Q5SJ76)
AQ, CQ: 1 - 1 (PDB: 4V51)
AQ, CQ: 2 - 105 (UniProt: Q5SHP7)
AR, CR: 1 - 1 (PDB: 4V51)
AR, CR: 2 - 88 (UniProt: Q5SLQ0)
AS, CS: 1 - 1 (PDB: 4V51)
AS, CS: 2 - 93 (UniProt: Q5SHP2)
AT, CT: 1 - 1 (PDB: 4V51)
AT, CT: 2 - 106 (UniProt: P80380)
AU, CU: 1 - 1 (PDB: 4V51)
AU, CU: 2 - 27 (UniProt: Q5SIH3)
B0, D0: 1 - 1 (PDB: 4V51)
B0, D0: 2 - 85 (UniProt: P60493)
B1, D1: 1 - 1 (PDB: 4V51)
B1, D1: 2 - 98 (UniProt: P60494)
B3, D3: 1 - 1 (PDB: 4V51)
B3, D3: 2 - 60 (UniProt: Q5SHQ6)
B5, D5: 1 - 1 (PDB: 4V51)
B5, D5: 2 - 60 (UniProt: P80339)
B6, D6: 1 - 1 (PDB: 4V51)
B6, D6: 2 - 54 (UniProt: P35871)
B8, D8: 1 - 1 (PDB: 4V51)
B8, D8: 2 - 65 (UniProt: P80341)
BC, DC: 0 - 0 (PDB: 4V51)
BC, DC: 1 - 228 (UniProt: Q5SLP7)
BD, DD: 1 - 1 (PDB: 4V51)
BD, DD: 2 - 276 (UniProt: P60405)
BG, DG: 1 - 1 (PDB: 4V51)
BG, DG: 2 - 182 (UniProt: Q5SHQ0)
BH, DH: 1 - 1 (PDB: 4V51)
BH, DH: 2 - 180 (UniProt: Q5SHQ3)
BS, DS: 1 - 1 (PDB: 4V51)
BS, DS: 2 - 112 (UniProt: Q5SHQ4)
BU, DU: 1 - 1 (PDB: 4V51)
BU, DU: 2 - 118 (UniProt: P60491)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 112 |
| Total formula weight | 4459231.4 | |
| Non-Polymers* | Number of molecules | 1385 |
| Total formula weight | 35009.5 | |
| All* | Total formula weight | 4494240.9 |
