4V4B
Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map.
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (AA) | 18S ribosomal RNA | polymer | 1507 | 489331.7 | 1 | GenBank (155076) | Saccharomyces cerevisiae (baker's yeast) | |
2 | B (AT) | Elongation factor 2 | polymer | 842 | 93407.1 | 1 | UniProt (P32324) Pfam (PF00009) Pfam (PF03144) Pfam (PF14492) Pfam (PF03764) Pfam (PF00679) | Saccharomyces cerevisiae (baker's yeast) | EF-2 |
3 | C (AB) | 40S ribosomal protein S0-A | polymer | 185 | 20355.4 | 1 | UniProt (P32905) Pfam (PF00318) | Saccharomyces cerevisiae (baker's yeast) | Nucleic acid-binding protein NAB1A |
4 | D (AC) | 40S ribosomal protein S3 | polymer | 192 | 21321.9 | 1 | UniProt (P05750) Pfam (PF07650) Pfam (PF00189) | Saccharomyces cerevisiae (baker's yeast) | YS3, RP13 |
5 | E (AD) | 40S ribosomal protein S9-A | polymer | 179 | 20363.4 | 1 | UniProt (O13516) Pfam (PF00163) Pfam (PF01479) | Saccharomyces cerevisiae (baker's yeast) | S13, YS11, RP21, YP28 |
6 | F (AE) | 40S ribosomal protein S2 | polymer | 149 | 15639.2 | 1 | UniProt (P25443) Pfam (PF00333) Pfam (PF03719) | Saccharomyces cerevisiae (baker's yeast) | S4, YS5, RP12, Omnipotent suppressor protein SUP44 |
7 | G (AG) | 40S ribosomal protein S5 | polymer | 150 | 16577.2 | 1 | UniProt (P26783) Pfam (PF00177) | Saccharomyces cerevisiae (baker's yeast) | S2, YS8, RP14 |
8 | H (AH) | 40S ribosomal protein S22 | polymer | 129 | 14518.9 | 1 | UniProt (P04648) | Saccharomyces cerevisiae (baker's yeast) | S24, YS22, RP50, YP58 |
9 | I (AI) | 40S ribosomal protein S16 | polymer | 142 | 15746.3 | 1 | UniProt (P40213) | Saccharomyces cerevisiae (baker's yeast) | RP61R |
10 | J (AJ) | 40S ribosomal protein S20 | polymer | 100 | 11352.2 | 1 | UniProt (P38701) Pfam (PF00338) | Saccharomyces cerevisiae (baker's yeast) | |
11 | K (AK) | 40S ribosomal protein S14-A | polymer | 136 | 14459.5 | 1 | UniProt (P06367) Pfam (PF00411) | Saccharomyces cerevisiae (baker's yeast) | RP59A |
12 | L (AL) | 40S ribosomal protein S23 | polymer | 118 | 12879.2 | 1 | UniProt (P32827) | Saccharomyces cerevisiae (baker's yeast) | S28, YS14, RP37 |
13 | M (AM) | 40S ribosomal protein S18 | polymer | 132 | 15485.8 | 1 | UniProt (P35271) | Saccharomyces cerevisiae (baker's yeast) | |
14 | N (AN) | 40S ribosomal protein S29-B | polymer | 36 | 4328.0 | 1 | UniProt (P41058) Pfam (PF00253) | Saccharomyces cerevisiae (baker's yeast) | S36, YS29 |
15 | O (AO) | 40S ribosomal protein S13 | polymer | 65 | 7841.4 | 1 | UniProt (P05756) Pfam (PF00312) | Saccharomyces cerevisiae (baker's yeast) | S27A, YS15 |
16 | P (AQ) | 40S ribosomal protein S11 | polymer | 76 | 8777.4 | 1 | UniProt (P26781) | Saccharomyces cerevisiae (baker's yeast) | S18, YS12, RP41 |
17 | Q (AS) | 40S ribosomal protein S15 | polymer | 80 | 8901.5 | 1 | UniProt (Q01855) Pfam (PF00203) | Saccharomyces cerevisiae (baker's yeast) | S21, YS21, RP52, RIG protein |
18 | R (B3) | 5.8S/25S ribosomal RNA | polymer | 2999 | 971012.3 | 1 | GenBank (3377778) | Saccharomyces cerevisiae (baker's yeast) | |
19 | S (B4) | 5S RIBOSOMAL RNA | polymer | 125 | 40298.0 | 1 | GenBank (3377779) | Saccharomyces cerevisiae (baker's yeast) | |
20 | T (BA) | 60S ribosomal protein L1 | polymer | 217 | 24524.8 | 1 | UniProt (P53030) | Saccharomyces cerevisiae (baker's yeast) | L10a |
21 | U (BB) | 60S ribosomal protein L2 | polymer | 253 | 27332.4 | 1 | UniProt (P05736) | Saccharomyces cerevisiae (baker's yeast) | YL6, L5, RP8 |
22 | V (BC) | 60S ribosomal protein L3 | polymer | 386 | 43719.6 | 1 | UniProt (P14126) Pfam (PF00297) | Saccharomyces cerevisiae (baker's yeast) | YL1, RP1, Trichodermin resistance protein |
23 | W (BD) | 60S ribosomal protein L4-B | polymer | 361 | 38997.9 | 1 | UniProt (P49626) Pfam (PF00573) Pfam (PF14374) | Saccharomyces cerevisiae (baker's yeast) | L2B, RP2 |
24 | X (BE) | 60S ribosomal protein L5 | polymer | 222 | 25444.4 | 1 | UniProt (P26321) Pfam (PF17144) | Saccharomyces cerevisiae (baker's yeast) | L1, YL3, Ribosomal 5S RNA-binding protein |
25 | Y (BF) | 60S ribosomal protein L7-A | polymer | 162 | 18452.7 | 1 | UniProt (P05737) Pfam (PF00327) | Saccharomyces cerevisiae (baker's yeast) | L6A, YL8A, RP11 |
26 | Z (BG) | 60S ribosomal protein L8-A | polymer | 119 | 12628.8 | 1 | UniProt (P17076) Pfam (PF01248) | Saccharomyces cerevisiae (baker's yeast) | L7A-2, L4-2, YL5, RP6 |
27 | AA (BH) | 60S ribosomal protein L9-A | polymer | 191 | 21605.1 | 1 | UniProt (P05738) Pfam (PF00347) | Saccharomyces cerevisiae (baker's yeast) | L8, YL11, RP25 |
28 | BA (BI) | 60S ribosomal protein L10 | polymer | 168 | 19249.5 | 1 | UniProt (P41805) Pfam (PF00252) | Saccharomyces cerevisiae (baker's yeast) | L9, Ubiquinol-cytochrome C reductase complex subunit VI requiring protein |
29 | CA (BJ) | 60S ribosomal protein L11 | polymer | 173 | 19624.5 | 1 | UniProt (P06380) | Saccharomyces cerevisiae (baker's yeast) | L16, YL16, 39A, RP39 |
30 | DA (BK) | 60S ribosomal protein L12 | polymer | 131 | 13953.3 | 1 | UniProt (P17079) | Saccharomyces cerevisiae (baker's yeast) | L15, YL23 |
31 | EA (BL) | 60S ribosomal protein L15-A | polymer | 203 | 24351.2 | 1 | UniProt (P05748) Pfam (PF00827) | Saccharomyces cerevisiae (baker's yeast) | YL10, L13, RP15R, YP18 |
32 | FA (BM) | 60S ribosomal protein L16-A | polymer | 146 | 16483.6 | 1 | UniProt (P26784) Pfam (PF00572) | Saccharomyces cerevisiae (baker's yeast) | L13A, RP22 |
33 | GA (BN) | 60S ribosomal protein L17-A | polymer | 183 | 20458.3 | 1 | UniProt (P05740) Pfam (PF00237) | Saccharomyces cerevisiae (baker's yeast) | YL17-A |
34 | HA (BO) | 60S ribosomal protein L18 | polymer | 120 | 13129.5 | 1 | UniProt (P07279) | Saccharomyces cerevisiae (baker's yeast) | RP28 |
35 | IA (BP) | 60S ribosomal protein L19 | polymer | 142 | 16318.1 | 1 | UniProt (P05735) | Saccharomyces cerevisiae (baker's yeast) | L23, YL14, RP33, RP15L |
36 | JA (BQ) | 60S ribosomal protein L21-A | polymer | 100 | 11609.6 | 1 | UniProt (Q02753) Pfam (PF01157) | Saccharomyces cerevisiae (baker's yeast) | |
37 | KA (BR) | 60S ribosomal protein L23 | polymer | 137 | 14494.0 | 1 | UniProt (P04451) | Saccharomyces cerevisiae (baker's yeast) | L17 |
38 | LA (BS) | 60S ribosomal protein L24-A | polymer | 56 | 6550.7 | 1 | UniProt (P04449) Pfam (PF01246) | Saccharomyces cerevisiae (baker's yeast) | L30A, RP29, YL21 |
39 | MA (BT) | 60S ribosomal protein L25 | polymer | 83 | 9480.1 | 1 | UniProt (P04456) Pfam (PF00276) | Saccharomyces cerevisiae (baker's yeast) | YL25, RP61L |
40 | NA (BU) | 60S ribosomal protein L26-A | polymer | 126 | 14134.6 | 1 | UniProt (P05743) Pfam (PF16906) Pfam (PF00467) | Saccharomyces cerevisiae (baker's yeast) | YL33 |
41 | OA (BV) | 60S ribosomal protein L28 | polymer | 148 | 16631.5 | 1 | UniProt (P02406) Pfam (PF00828) | Saccharomyces cerevisiae (baker's yeast) | L27A, L29, YL24, RP62 |
42 | PA (B0) | 60S ribosomal protein L32 | polymer | 130 | 14809.4 | 1 | UniProt (P38061) Pfam (PF01655) | Saccharomyces cerevisiae (baker's yeast) | |
43 | QA (BW) | 60S ribosomal protein L31 | polymer | 112 | 12849.0 | 1 | UniProt (P04649) | Saccharomyces cerevisiae (baker's yeast) | L34, YL28 |
44 | RA (BX) | 60S ribosomal protein L35 | polymer | 120 | 13942.6 | 1 | UniProt (P39741) | Saccharomyces cerevisiae (baker's yeast) | |
45 | SA (BY) | 60S ribosomal protein L37-A | polymer | 87 | 9746.2 | 1 | UniProt (P49166) Pfam (PF01907) | Saccharomyces cerevisiae (baker's yeast) | L35, YP55 |
46 | TA (BZ) | 60S ribosomal protein L42 | polymer | 105 | 12115.5 | 1 | UniProt (P02405) | Saccharomyces cerevisiae (baker's yeast) | L44, YL27, YP44, L41 |
47 | UA (B9) | 60S ribosomal protein L43 | polymer | 91 | 9981.8 | 1 | UniProt (P49631) | Saccharomyces cerevisiae (baker's yeast) | L37A, YL35 |
Sequence modifications
AJ: 21 - 120 (UniProt: P38701)
B3: 1 - 2914 (GenBank: 3377778)
PDB | External Database | Details |
---|---|---|
- | Val 116 | deletion |
PDB | External Database | Details |
---|---|---|
C 73 | U 2591 | conflict |
A 74 | G 2592 | conflict |
U 103 | C 2621 | conflict |
G 104 | A 2622 | conflict |
- | U 2639 | deletion |
- | C 2640 | deletion |
C 130 | - | insertion |
U 131 | - | insertion |
U 200 | C 2718 | conflict |
C 300 | U 2818 | conflict |
G 301 | C 2819 | conflict |
C 318 | U 2836 | conflict |
C 350 | G 2868 | conflict |
G 351 | A 2869 | conflict |
A 363 | C 2881 | conflict |
C 364 | U 2882 | conflict |
C 560 | U 3078 | conflict |
C 574 | G 3092 | conflict |
G 575 | A 3093 | conflict |
C 582 | U 3100 | conflict |
G 583 | C 3101 | conflict |
C 653 | U 3171 | conflict |
C 972 | - | insertion |
U 973 | - | insertion |
A 974 | - | insertion |
G 976 | - | insertion |
G 976 | - | insertion |
G 977 | - | insertion |
G 978 | - | insertion |
G 979 | - | insertion |
C 980 | - | insertion |
C 981 | - | insertion |
C 982 | - | insertion |
A 983 | - | insertion |
C 984 | - | insertion |
C 985 | - | insertion |
A 986 | - | insertion |
G 987 | - | insertion |
C 988 | - | insertion |
C 989 | - | insertion |
U 990 | - | insertion |
A 991 | - | insertion |
C 992 | - | insertion |
C 993 | - | insertion |
A 994 | - | insertion |
A 995 | - | insertion |
C 1026 | U 3544 | conflict |
U 1162 | G 3680 | conflict |
U 1165 | G 3683 | conflict |
G 1166 | A 3684 | conflict |
C 1180 | U 3698 | conflict |
U 1182 | C 3700 | conflict |
A 1184 | C 3702 | conflict |
U 1186 | C 3704 | conflict |
A 1190 | G 3708 | conflict |
G 1191 | A 3709 | conflict |
G 1193 | A 3711 | conflict |
U 1194 | A 3712 | conflict |
C 1206 | U 3724 | conflict |
U 1320 | C 3838 | conflict |
U 1326 | C 3844 | conflict |
A 1329 | G 3847 | conflict |
A 1331 | G 3849 | conflict |
A 1337 | G 3855 | conflict |
A 1479 | G 3997 | conflict |
U 1480 | A 3998 | conflict |
G 1496 | A 4014 | conflict |
U 1587 | A 4105 | conflict |
A 1669 | G 4187 | conflict |
G 1670 | A 4188 | conflict |
C 1949 | G 4467 | conflict |
C 1950 | G 4468 | conflict |
A 1959 | G 4477 | conflict |
G 1962 | C 4480 | conflict |
G 1963 | C 4481 | conflict |
C 1966 | U 4484 | conflict |
U 2137 | A 4655 | conflict |
U 2139 | G 4657 | conflict |
G 3145 | - | insertion |
G 2146 | - | insertion |
G 2147 | - | insertion |
G 2148 | - | insertion |
A 2149 | - | insertion |
U 2150 | - | insertion |
G 2151 | - | insertion |
C 2152 | - | insertion |
G 2153 | - | insertion |
U 2154 | - | insertion |
A 2155 | - | insertion |
G 2156 | - | insertion |
G 2157 | - | insertion |
A 2158 | - | insertion |
U 2159 | - | insertion |
A 2160 | - | insertion |
G 2161 | - | insertion |
G 2162 | - | insertion |
U 2163 | - | insertion |
G 2164 | - | insertion |
G 2165 | - | insertion |
G 2166 | - | insertion |
A 2167 | - | insertion |
G 2168 | - | insertion |
C 2169 | - | insertion |
G 2170 | - | insertion |
C 2171 | - | insertion |
A 2203 | - | insertion |
A 2204 | - | insertion |
G 2205 | - | insertion |
C 2206 | - | insertion |
G 2207 | - | insertion |
C 2208 | - | insertion |
C 2209 | - | insertion |
G 2210 | - | insertion |
G 2211 | - | insertion |
U 2212 | - | insertion |
G 2213 | - | insertion |
A 2214 | - | insertion |
A 2215 | - | insertion |
A 2216 | - | insertion |
U 2217 | - | insertion |
A 2218 | - | insertion |
C 2219 | - | insertion |
C 2220 | - | insertion |
A 2221 | - | insertion |
C 2222 | - | insertion |
C 2223 | - | insertion |
C 2224 | - | insertion |
U 2225 | - | insertion |
U 2226 | - | insertion |
C 2227 | - | insertion |
C 2228 | - | insertion |
C 2229 | - | insertion |
C 2230 | - | insertion |
G 2231 | - | insertion |
G 2232 | - | insertion |
C 2233 | - | insertion |
U 2234 | - | insertion |
G 2235 | - | insertion |
G 2236 | - | insertion |
C 2325 | U 4843 | conflict |
U 2326 | C 4844 | conflict |
G 2341 | A 4859 | conflict |
A 2374 | G 4892 | conflict |
G 2375 | A 4893 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 47 |
Total formula weight | 2305214.9 | |
All* | Total formula weight | 2305214.9 |