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4V4B

Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(AA)
18S ribosomal RNApolymer1507489331.71GenBank (155076)Saccharomyces cerevisiae (baker's yeast)
2B
(AT)
Elongation factor 2polymer84293407.11UniProt (P32324)
Pfam (PF00009)
Pfam (PF03144)
Pfam (PF14492)
Pfam (PF03764)
Pfam (PF00679)
Saccharomyces cerevisiae (baker's yeast)EF-2
3C
(AB)
40S ribosomal protein S0-Apolymer18520355.41UniProt (P32905)
Pfam (PF00318)
Saccharomyces cerevisiae (baker's yeast)Nucleic acid-binding protein NAB1A
4D
(AC)
40S ribosomal protein S3polymer19221321.91UniProt (P05750)
Pfam (PF07650)
Pfam (PF00189)
Saccharomyces cerevisiae (baker's yeast)YS3, RP13
5E
(AD)
40S ribosomal protein S9-Apolymer17920363.41UniProt (O13516)
Pfam (PF00163)
Pfam (PF01479)
Saccharomyces cerevisiae (baker's yeast)S13, YS11, RP21, YP28
6F
(AE)
40S ribosomal protein S2polymer14915639.21UniProt (P25443)
Pfam (PF00333)
Pfam (PF03719)
Saccharomyces cerevisiae (baker's yeast)S4, YS5, RP12, Omnipotent suppressor protein SUP44
7G
(AG)
40S ribosomal protein S5polymer15016577.21UniProt (P26783)
Pfam (PF00177)
Saccharomyces cerevisiae (baker's yeast)S2, YS8, RP14
8H
(AH)
40S ribosomal protein S22polymer12914518.91UniProt (P04648)Saccharomyces cerevisiae (baker's yeast)S24, YS22, RP50, YP58
9I
(AI)
40S ribosomal protein S16polymer14215746.31UniProt (P40213)Saccharomyces cerevisiae (baker's yeast)RP61R
10J
(AJ)
40S ribosomal protein S20polymer10011352.21UniProt (P38701)
Pfam (PF00338)
Saccharomyces cerevisiae (baker's yeast)
11K
(AK)
40S ribosomal protein S14-Apolymer13614459.51UniProt (P06367)
Pfam (PF00411)
Saccharomyces cerevisiae (baker's yeast)RP59A
12L
(AL)
40S ribosomal protein S23polymer11812879.21UniProt (P32827)Saccharomyces cerevisiae (baker's yeast)S28, YS14, RP37
13M
(AM)
40S ribosomal protein S18polymer13215485.81UniProt (P35271)Saccharomyces cerevisiae (baker's yeast)
14N
(AN)
40S ribosomal protein S29-Bpolymer364328.01UniProt (P41058)
Pfam (PF00253)
Saccharomyces cerevisiae (baker's yeast)S36, YS29
15O
(AO)
40S ribosomal protein S13polymer657841.41UniProt (P05756)
Pfam (PF00312)
Saccharomyces cerevisiae (baker's yeast)S27A, YS15
16P
(AQ)
40S ribosomal protein S11polymer768777.41UniProt (P26781)Saccharomyces cerevisiae (baker's yeast)S18, YS12, RP41
17Q
(AS)
40S ribosomal protein S15polymer808901.51UniProt (Q01855)
Pfam (PF00203)
Saccharomyces cerevisiae (baker's yeast)S21, YS21, RP52, RIG protein
18R
(B3)
5.8S/25S ribosomal RNApolymer2999971012.31GenBank (3377778)Saccharomyces cerevisiae (baker's yeast)
19S
(B4)
5S RIBOSOMAL RNApolymer12540298.01GenBank (3377779)Saccharomyces cerevisiae (baker's yeast)
20T
(BA)
60S ribosomal protein L1polymer21724524.81UniProt (P53030)Saccharomyces cerevisiae (baker's yeast)L10a
21U
(BB)
60S ribosomal protein L2polymer25327332.41UniProt (P05736)Saccharomyces cerevisiae (baker's yeast)YL6, L5, RP8
22V
(BC)
60S ribosomal protein L3polymer38643719.61UniProt (P14126)
Pfam (PF00297)
Saccharomyces cerevisiae (baker's yeast)YL1, RP1, Trichodermin resistance protein
23W
(BD)
60S ribosomal protein L4-Bpolymer36138997.91UniProt (P49626)
Pfam (PF00573)
Pfam (PF14374)
Saccharomyces cerevisiae (baker's yeast)L2B, RP2
24X
(BE)
60S ribosomal protein L5polymer22225444.41UniProt (P26321)
Pfam (PF17144)
Saccharomyces cerevisiae (baker's yeast)L1, YL3, Ribosomal 5S RNA-binding protein
25Y
(BF)
60S ribosomal protein L7-Apolymer16218452.71UniProt (P05737)
Pfam (PF00327)
Saccharomyces cerevisiae (baker's yeast)L6A, YL8A, RP11
26Z
(BG)
60S ribosomal protein L8-Apolymer11912628.81UniProt (P17076)
Pfam (PF01248)
Saccharomyces cerevisiae (baker's yeast)L7A-2, L4-2, YL5, RP6
27AA
(BH)
60S ribosomal protein L9-Apolymer19121605.11UniProt (P05738)
Pfam (PF00347)
Saccharomyces cerevisiae (baker's yeast)L8, YL11, RP25
28BA
(BI)
60S ribosomal protein L10polymer16819249.51UniProt (P41805)
Pfam (PF00252)
Saccharomyces cerevisiae (baker's yeast)L9, Ubiquinol-cytochrome C reductase complex subunit VI requiring protein
29CA
(BJ)
60S ribosomal protein L11polymer17319624.51UniProt (P06380)Saccharomyces cerevisiae (baker's yeast)L16, YL16, 39A, RP39
30DA
(BK)
60S ribosomal protein L12polymer13113953.31UniProt (P17079)Saccharomyces cerevisiae (baker's yeast)L15, YL23
31EA
(BL)
60S ribosomal protein L15-Apolymer20324351.21UniProt (P05748)
Pfam (PF00827)
Saccharomyces cerevisiae (baker's yeast)YL10, L13, RP15R, YP18
32FA
(BM)
60S ribosomal protein L16-Apolymer14616483.61UniProt (P26784)
Pfam (PF00572)
Saccharomyces cerevisiae (baker's yeast)L13A, RP22
33GA
(BN)
60S ribosomal protein L17-Apolymer18320458.31UniProt (P05740)
Pfam (PF00237)
Saccharomyces cerevisiae (baker's yeast)YL17-A
34HA
(BO)
60S ribosomal protein L18polymer12013129.51UniProt (P07279)Saccharomyces cerevisiae (baker's yeast)RP28
35IA
(BP)
60S ribosomal protein L19polymer14216318.11UniProt (P05735)Saccharomyces cerevisiae (baker's yeast)L23, YL14, RP33, RP15L
36JA
(BQ)
60S ribosomal protein L21-Apolymer10011609.61UniProt (Q02753)
Pfam (PF01157)
Saccharomyces cerevisiae (baker's yeast)
37KA
(BR)
60S ribosomal protein L23polymer13714494.01UniProt (P04451)Saccharomyces cerevisiae (baker's yeast)L17
38LA
(BS)
60S ribosomal protein L24-Apolymer566550.71UniProt (P04449)
Pfam (PF01246)
Saccharomyces cerevisiae (baker's yeast)L30A, RP29, YL21
39MA
(BT)
60S ribosomal protein L25polymer839480.11UniProt (P04456)
Pfam (PF00276)
Saccharomyces cerevisiae (baker's yeast)YL25, RP61L
40NA
(BU)
60S ribosomal protein L26-Apolymer12614134.61UniProt (P05743)
Pfam (PF16906)
Pfam (PF00467)
Saccharomyces cerevisiae (baker's yeast)YL33
41OA
(BV)
60S ribosomal protein L28polymer14816631.51UniProt (P02406)
Pfam (PF00828)
Saccharomyces cerevisiae (baker's yeast)L27A, L29, YL24, RP62
42PA
(B0)
60S ribosomal protein L32polymer13014809.41UniProt (P38061)
Pfam (PF01655)
Saccharomyces cerevisiae (baker's yeast)
43QA
(BW)
60S ribosomal protein L31polymer11212849.01UniProt (P04649)Saccharomyces cerevisiae (baker's yeast)L34, YL28
44RA
(BX)
60S ribosomal protein L35polymer12013942.61UniProt (P39741)Saccharomyces cerevisiae (baker's yeast)
45SA
(BY)
60S ribosomal protein L37-Apolymer879746.21UniProt (P49166)
Pfam (PF01907)
Saccharomyces cerevisiae (baker's yeast)L35, YP55
46TA
(BZ)
60S ribosomal protein L42polymer10512115.51UniProt (P02405)Saccharomyces cerevisiae (baker's yeast)L44, YL27, YP44, L41
47UA
(B9)
60S ribosomal protein L43polymer919981.81UniProt (P49631)Saccharomyces cerevisiae (baker's yeast)L37A, YL35
Sequence modifications
AJ: 21 - 120 (UniProt: P38701)
PDBExternal DatabaseDetails
-Val 116deletion
B3: 1 - 2914 (GenBank: 3377778)
PDBExternal DatabaseDetails
C 73U 2591conflict
A 74G 2592conflict
U 103C 2621conflict
G 104A 2622conflict
-U 2639deletion
-C 2640deletion
C 130-insertion
U 131-insertion
U 200C 2718conflict
C 300U 2818conflict
G 301C 2819conflict
C 318U 2836conflict
C 350G 2868conflict
G 351A 2869conflict
A 363C 2881conflict
C 364U 2882conflict
C 560U 3078conflict
C 574G 3092conflict
G 575A 3093conflict
C 582U 3100conflict
G 583C 3101conflict
C 653U 3171conflict
C 972-insertion
U 973-insertion
A 974-insertion
G 976-insertion
G 976-insertion
G 977-insertion
G 978-insertion
G 979-insertion
C 980-insertion
C 981-insertion
C 982-insertion
A 983-insertion
C 984-insertion
C 985-insertion
A 986-insertion
G 987-insertion
C 988-insertion
C 989-insertion
U 990-insertion
A 991-insertion
C 992-insertion
C 993-insertion
A 994-insertion
A 995-insertion
C 1026U 3544conflict
U 1162G 3680conflict
U 1165G 3683conflict
G 1166A 3684conflict
C 1180U 3698conflict
U 1182C 3700conflict
A 1184C 3702conflict
U 1186C 3704conflict
A 1190G 3708conflict
G 1191A 3709conflict
G 1193A 3711conflict
U 1194A 3712conflict
C 1206U 3724conflict
U 1320C 3838conflict
U 1326C 3844conflict
A 1329G 3847conflict
A 1331G 3849conflict
A 1337G 3855conflict
A 1479G 3997conflict
U 1480A 3998conflict
G 1496A 4014conflict
U 1587A 4105conflict
A 1669G 4187conflict
G 1670A 4188conflict
C 1949G 4467conflict
C 1950G 4468conflict
A 1959G 4477conflict
G 1962C 4480conflict
G 1963C 4481conflict
C 1966U 4484conflict
U 2137A 4655conflict
U 2139G 4657conflict
G 3145-insertion
G 2146-insertion
G 2147-insertion
G 2148-insertion
A 2149-insertion
U 2150-insertion
G 2151-insertion
C 2152-insertion
G 2153-insertion
U 2154-insertion
A 2155-insertion
G 2156-insertion
G 2157-insertion
A 2158-insertion
U 2159-insertion
A 2160-insertion
G 2161-insertion
G 2162-insertion
U 2163-insertion
G 2164-insertion
G 2165-insertion
G 2166-insertion
A 2167-insertion
G 2168-insertion
C 2169-insertion
G 2170-insertion
C 2171-insertion
A 2203-insertion
A 2204-insertion
G 2205-insertion
C 2206-insertion
G 2207-insertion
C 2208-insertion
C 2209-insertion
G 2210-insertion
G 2211-insertion
U 2212-insertion
G 2213-insertion
A 2214-insertion
A 2215-insertion
A 2216-insertion
U 2217-insertion
A 2218-insertion
C 2219-insertion
C 2220-insertion
A 2221-insertion
C 2222-insertion
C 2223-insertion
C 2224-insertion
U 2225-insertion
U 2226-insertion
C 2227-insertion
C 2228-insertion
C 2229-insertion
C 2230-insertion
G 2231-insertion
G 2232-insertion
C 2233-insertion
U 2234-insertion
G 2235-insertion
G 2236-insertion
C 2325U 4843conflict
U 2326C 4844conflict
G 2341A 4859conflict
A 2374G 4892conflict
G 2375A 4893conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains47
Total formula weight2305214.9
All*Total formula weight2305214.9
*Water molecules are not included.

227111

PDB entries from 2024-11-06

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