4UZQ
STRUCTURE OF THE WNT DEACYLASE NOTUM IN COMPLEX WITH O-PALMITOLEOYL SERINE - CRYSTAL FORM IX - 1.5A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN NOTUM HOMOLOG | polymer | 386 | 43974.5 | 1 | UniProt (Q6P988) Pfam (PF03283) | HOMO SAPIENS (HUMAN) | NOTUM |
| 2 | B (B) | PROTEIN WNT-7A | polymer | 8 | 749.8 | 1 | UniProt (O00755) | HOMO SAPIENS | |
| 3 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | D, E (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | F, G, H (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 6 | I (B) | PALMITOLEIC ACID | non-polymer | 254.4 | 1 | Chemie (PAM) | |||
| 7 | J (A) | water | water | 18.0 | 305 | Chemie (HOH) |
Sequence modifications
A: 81 - 451 (UniProt: Q6P988)
| PDB | External Database | Details |
|---|---|---|
| Glu 78 | - | expression tag |
| Thr 79 | - | expression tag |
| Gly 80 | - | expression tag |
| Gly 452 | - | expression tag |
| Thr 453 | - | expression tag |
| His 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
| His 457 | - | expression tag |
| His 458 | - | expression tag |
| His 459 | - | expression tag |
| His 460 | - | expression tag |
| His 461 | - | expression tag |
| His 462 | - | expression tag |
| His 463 | - | expression tag |
| Ala 232 | Ser 232 | engineered mutation |
| Ser 330 | Cys 330 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44724.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 628.0 | |
| All* | Total formula weight | 45352.3 |
