4UZA

STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VIII - PHOSPHATE COMPLEX - 2.4A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PROTEIN NOTUM HOMOLOG	polymer	383	43426.9	1	UniProt (Q6P988) Pfam (PF03283)	HOMO SAPIENS (HUMAN)
2	B (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
3	C (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
4	D (A)	water	water		18.0	23	Chemie (HOH)

Sequence modifications

A: 80 - 452 (UniProt: Q6P988)

PDB	External Database	Details
Glu 78	-	expression tag
Thr 79	-	expression tag
Thr 453	-	expression tag
Lys 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag
His 459	-	expression tag
His 460	-	expression tag
Ser 144	Arg 144	engineered mutation
Ser 145	Arg 145	engineered mutation
Ser 330	Cys 330	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43426.9
Non-Polymers*	Number of molecules	2
	Total formula weight	316.2
All*	Total formula weight	43743.1

*Water molecules are not included.